Gerhard Pfleiderer

Gerhard Pfleiderer (born February 20, 1921 in Heilbronn ; † January 13, 2008 in Korntal ) was a German biochemist .

Life

Pfleiderer studied chemistry at the Ludwig Maximilians University in Munich from 1939 , but had to drop out in 1940. He was exempt from military service because he had a Jewish mother - a cousin of Otto Meyerhof . In 1946 he continued his studies at the University of Heidelberg . In 1949 he received his doctorate at the Max Planck Institute for Medicine in Heidelberg under Richard Kuhn , whereby he had to take the exam in 1952 in Frankfurt under Theodor Wieland . He then went to Wieland's research group in Frankfurt, who sent him to Theodor Bücher in Hamburg to study enzymology . In 1957 he completed his habilitation at the Goethe University in Frankfurt am Main and was in Mainz from 1959. In 1961 he became an associate professor and in 1965 a full professor in Frankfurt. In 1969 he became professor of biochemistry at the newly founded Ruhr University Bochum and in 1975 at the University of Stuttgart . In 1973 he was elected a member of the Leopoldina . In 1988 he retired.

He dealt with enzymes and enzyme diagnostics with immunological methods with applications in cancer diagnostics, for example with the changes in the isoenzyme pattern. The discovery of creatine kinase MB became important in the diagnosis of heart disease and the role of acid phosphatase (PSP or SPP) in the diagnosis of prostate cancer. He also held a patent for the determination of glucose in blood.

With Wieland he played a role in clarifying the term isoenzyme (introduced by Clement Markert, Møller, Yale University 1959).

literature

• Winfried R. Pötsch (lead), Annelore Fischer, Wolfgang Müller: Lexicon of important chemists , Harri Deutsch 1989, p. 343
• Wolfgang Trommer, obituary for Gerhard Pfleiderer, Biospektrum 2009, pdf

Individual evidence

1. ^ Member entry by Gerhard Pfleiderer at the German Academy of Natural Scientists Leopoldina , accessed on February 7, 2016.