Harry C. Dietz

Harry C. Dietz

Harry C. "Hal" Dietz is an American geneticist , pediatric cardiologist, and cardiovascular researcher at Johns Hopkins University . There he holds a professorship named after Victor Almon McKusick and is director of the William S. Smilow Center for Marfan Research . Since 1997 Dietz has also been doing research for the Howard Hughes Medical Institute .

Dietz graduated from the Duke University a Bachelor in Medical Technology and in 1984 at the State University of New York Upstate Medical University (part of the State University of New York ) an MD as the conclusion of the medical school .

Dietz is best known for his contributions to the genetics and pathophysiology of Marfan syndrome . He discovered that the disease is based on a disorder in the fibrillin- 1 gene, which on the one hand is a structural protein and on the other hand inhibits the growth factor TGF-β . His work led to a deeper understanding of the causes of the aortic aneurysm , to the improvement of drug therapy (with losartan , which also inhibits TGF-β) and to the development of a blood test that should indicate the right time for operative treatment of this disease. In 2005 Dietz - together with Bart L. Loeys - was the first to describe the Loeys-Dietz syndrome . Other works by Dietz deal with Duchenne muscular dystrophy and scleroderma .

Awards (selection)

• 2006 Curt Stern Award from the American Society of Human Genetics
• 2011 member of the National Academy of Sciences
• 2013 Pasarow Award for cardiovascular research
• 2014 Harrington Prize for Innovation in Medicine from the American Society for Clinical Investigation
• 2014 InBev-Baillet Latour Health Prize
• 2017 President of the American Society of Human Genetics

Web links

• Harry C Dietz, III, MD at Johns Hopkins University (hopkinsmedicine.org)
• Harry C. Dietz, MD at the Cellular and Molecular Medicine Program at the Johns Hopkins School of Medicine (jhmi.edu)
• Harry C. Dietz, MD at the Howard Hughes Medical Institute (hhmi.org)

Individual evidence

1. ^ Victor A. McKusick : Introductory Speech for Hal Dietz. In: The American Journal of Human Genetics. 81, 2007, p. 660, doi: 10.1086 / 521408 .
2. ^ Past ASHG Award Recipients. In: ashg.org. Retrieved October 21, 2017 (English). 
3. ↑ Harry Dietz. In: nasonline.org. Retrieved October 17, 2017 . 
4. ↑ The 2014 Harrington Prize for Innovation in Medicine: Harry C. Dietz, MD - The American Society for Clinical Investigation. In: the-asci.org. Retrieved October 17, 2017 . 
5. ↑ 2014 Harrington Prize Recipient. In: uhhospitals.org. Retrieved October 17, 2017 . 
6. ↑ Le Prix Baillet Latour de la Santé - Tous les lauréats (PDF; 674 kB); accessed on October 17, 2017.
7. ↑ 2017 ASHG Board of Directors - ASHG. In: ashg.org. Retrieved October 17, 2017 .