Homocysteic acid

Structural formula
General
Surname	Homocysteic acid
other names	L -2-amino-4-sulfobutyric acid Homocysteat
Molecular formula	C 4 H 9 NO 5 S
External identifiers / databases
CAS number 14857-77-3 PubChem 177491 ChemSpider 154529 Wikidata Q15410991
properties
Molar mass	183.18 g mol −1
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

L- homocysteic acid is a chemical compound from the group of non-proteinogenic amino acids .

properties

L- homocysteic acid is the oxidation product of L - homocysteine . It is an analogue of L - glutamic acid . L- homocysteic acid activates the NMDA receptor .

L- homocysteic acid activates the glutamate receptor on the tongue and triggers an umami taste.

Individual evidence

1. ↑ L-Homocysteic acid data sheet , from Sigma-Aldrich , accessed on October 3, 2018 ( PDF ).
2. ^ JW Olney, MT Price, KS Salles, J. Labruyere, R. Ryerson, K. Mahan, G. Friedrich, L. Samson: L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor. In: Brain research bulletin. Volume 19, Number 5, November 1987, pp. 597-602, PMID 2891418 .
3. ^ JW Olney, MT Price, KS Salles, J. Labruyere, R. Ryerson, K. Mahan, G. Friedrich, L. Samson: L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor. In: Brain research bulletin. Volume 19, Number 5, November 1987, pp. 597-602, PMID 2891418 .
4. ↑ M. Yuzaki, JA Connor: Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice. In: Journal of neurophysiology. Volume 82, Number 5, November 1999, pp. 2820-2826, doi : 10.1152 / jn.1999.82.5.2820 , PMID 10561449 .
5. ↑ Hans-Dieter Belitz , Werner Grosch : Textbook of food chemistry. Springer-Verlag, 2007, ISBN 978-3-540-73202-0 , p. 442.