Iscotrizinol

Structural formula
	Structural formula without stereochemistry
General
Surname	Iscotrizinol
other names	Bis (2-ethylhexyl) -4,4 ′ - {[6 - ({4 - [(2-methyl-2-propanyl) carbamoyl] phenyl} amino) 1,3,5-triazine-2,4-diyl] diimino} dibenzoate ( IUPAC ) ; 4,6-bis [4- (2-ethylhexyloxycarbonyl) anilino] -2- [4- ( tert -butylaminocarbonyl) anilino] -1,3,5-triazine; DIETHYLHEXYL BUTAMIDO TRIAZONE ( INCI ) ; Diethylhexylbutamidotriazone;
Molecular formula	C 44 H 59 N 7 O 5
Brief description	light yellow to beige, crystalline powder
External identifiers / databases
EC number	421-450-8
ECHA InfoCard	100.102.002
PubChem	9810816
ChemSpider	7986571
Wikidata	Q6079473
properties
Molar mass	765.98 g mol −1
Physical state	firmly
safety instructions
GHS labeling of hazardous substances	no GHS pictograms
	no GHS pictograms
H and P phrases	H: no H-phrases
	P: no P-phrases
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Iscotrizinol ( USAN ) is a organische- chemical compound , which in sunscreens is used to UVB - and a part of the UVA radiation to absorb. The best protection is at 310 nm . It is one of the most photostable chemical sunscreens known today as it takes 25 hours to lose 10% of its photoprotective ability. It is marketed as Uvasorb HEB by 3V Sigma.

The molecule has two stereocenters , there are three stereoisomers :

( R , R ) -form,
( S , S ) -form and
meso shape.

Individual evidence

↑ Entry on DIETHYLHEXYL BUTAMIDO TRIAZONE in the CosIng database of the EU Commission, accessed on January 28, 2020.
↑ ^a ^b ^c data sheet Iscotrizinol, analytical standard at Sigma-Aldrich , accessed on January 24, 2020 ( PDF ).
↑ Statement on a nonproprietary name adopted by the USAN Council
↑ incidecoder.com: Diethylhexyl Butamido Triazone
↑ Couteau C, Pommier M, Paparis E, Coiffard LJ: Study of the efficacy of 18 sun filters authorized in European Union tested in vitro . In: Pharmacy . 62, June 2007, pp. 449-452. doi : 10.1691 / ph.2007.6.6247 . PMID 17663193 .
↑ Couteau C, Faure A, Fortin J, Paparis E, Coiffard LJ: Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro . In: Journal of Pharmaceutical and Biomedical Analysis . 44, May 2007, pp. 270-273. doi : 10.1016 / j.jpba.2007.01.052 .

[CosIng-1] Entry on DIETHYLHEXYL BUTAMIDO TRIAZONE in the CosIng database of the EU Commission, accessed on January 28, 2020.

[Sigma-2] ta sheet Iscotrizinol, analytical standard at Sigma-Aldrich , accessed on January 24, 2020 ( PDF ).

[3] Statement on a nonproprietary name adopted by the USAN Council

[4] r.com: Diethylhexyl Butamido Triazone

[5] Couteau C, Pommier M, Paparis E, Coiffard LJ: Study of the efficacy of 18 sun filters authorized in European Union tested in vitro . In: Pharmacy . 62, June 2007, pp. 449-452. doi : 10.1691 / ph.2007.6.6247 . PMID 17663193 .

[6] Couteau C, Faure A, Fortin J, Paparis E, Coiffard LJ: Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro . In: Journal of Pharmaceutical and Biomedical Analysis . 44, May 2007, pp. 270-273. doi : 10.1016 / j.jpba.2007.01.052 .