Jutta Gardener

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Jutta Gärtner (born April 14, 1961 in Rheinhausen) is a German pediatrician and professor at the University of Göttingen .

Career

Gärtner studied and obtained his doctorate in medicine at the Université Catholique de Louvain in Belgium and the University of Hamburg . She then spent several years at the Johns Hopkins University School of Medicine and at the Johns Hopkins Hospital in Baltimore in the USA before moving to the Heinrich Heine University in Düsseldorf in 1993. In 1995 she qualified as a professor there, received the Venia legendi for pediatrics and became a specialist in paediatrics. From 1995 to 2000 she was an adjunct professor for pediatrics and neuropediatrics at the Heinrich Heine University in Düsseldorf before she was appointed professor for pediatrics and neuropediatrics in 2000.

Since 2002 she has been director of the Clinic for Pediatric and Adolescent Medicine at Göttingen University Medical Center . Since 2008 she has headed the German Center for Multiple Sclerosis in Children and Adolescents together with Wolfgang Brück .

She is a member of the scientific advisory board of the Von Behring Röntgen Foundation , a member of the Commission for Drugs for Children and Adolescents (KAKJ) of the Federal Institute for Drugs and Medical Devices (BfArM) and a member of the medical advisory board of the German Multiple Sclerosis Society .

research

Gärtner's research focuses on rare genetic diseases of the nervous system in children and adolescents and their treatment. She is an expert on multiple sclerosis in children and was responsible for the development of the guidelines on pediatric multiple sclerosis.

Since the child's organism reacts differently than that of an adult, she is investigating possible therapies in various studies, such as B. the administration of interferon beta-1a , natalizumab and fingolimod .

Gärtner researches the genetic causes of congenital, neurodegenerative diseases . In this way, she was able to determine the underlying gene mutations for some diseases , such as B. Mutations in the Cathepsin D gene, in the L1CAM gene or in the PMP70 gene . She was able to trace the genetic cause of a disease similar to Pelizaeus-Merzbacher disease back to various mutations in the connexin 46.6 ( GJA12) gene.

For the Zellweger syndrome , she was able to identify mutations in genes that are necessary for the development of peroxisomes as the genetic cause .

Awards

Web links

Individual evidence

  1. ^ From Behring-Röntgen-Stiftung: Organization. Retrieved May 23, 2020 .
  2. ↑ BfArM - Commission for Drugs for Children and Young People (KAKJ) - Members of the Commission for Drugs for Children and Young People (KAKJ). Retrieved May 23, 2020 .
  3. ↑ Medical Advisory Board of the DMSG. Retrieved May 23, 2020 .
  4. ↑ AWMF: Guidelines for Pediatric Multiple Sclerosis. Retrieved May 23, 2020 .
  5. ↑ Daniela Pohl, Kevin Rostasy, Jutta gardener Folker Hanefeld: Treatment of early onset multiple sclerosis with subcutaneous interferon beta-1a. In: Neurology. 64, 2005, p. 888, doi : 10.1212 / 01.WNL.0000153570.33845.6A .
  6. ↑ Peter Huppke, Wiebke Stark, Claudia Zürcher, Brenda Huppke, Wolfgang Brück, Jutta Gärtner: Natalizumab Use in Pediatric Multiple Sclerosis. In: Archives of Neurology. 65, 2008, doi : 10.1001 / archneur . 65.12.1655 .
  7. ↑ Tanuja Chitnis, Douglas L. Arnold, Brenda Banwell, Wolfgang Brück, Angelo Ghezzi, Gavin Giovannoni, Benjamin Greenberg, Lauren Krupp, Kevin Rostásy, Marc Tardieu, Emmanuelle Waubant, Jerry S. Wolinsky, Amit Bar-Or, Tracy Stites, Y . u. Chen, Norman Putzki, Martin Merschhemke, Jutta Gärtner: Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis. In: New England Journal of Medicine. 379, 2018, p. 1017, doi : 10.1056 / NEJMoa1800149 .
  8. ↑ Robert Steinfeld, Konstanze Reinhardt, Kathrin Schreiber, Merle Hillebrand, Ralph Kraetzner, Wolfgang Brück, Paul Saftig, Jutta Gärtner: Cathepsin D Deficiency Is Associated with a Human Neurodegenerative Disorder. In: The American Journal of Human Genetics. 78, 2006, p. 988, doi : 10.1086 / 504159 .
  9. ↑ Sabine Weller, Jutta Gärtner: Genetic and clinical aspects of X-linked hydrocephalus (L1 disease): Mutations in the gene. In: Human Mutation. 18, 2001, p. 1, doi : 10.1002 / humu.1144 .
  10. ↑ Jutta Gärtner, Hugo Moser, David Valle: Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. In: Nature Genetics. 1, 1992, p. 16, doi : 10.1038 / ng0492-16 .
  11. ↑ Birgit Uhlenberg, Markus Schuelke, Franz Rüschendorf, Nico Ruf, Angela M. Kaindl, Marco Henneke, Holger Thiele, Gisela Stoltenburg-Didinger, Fuat Aksu, Haluk Topaloğlu, Peter Nürnberg, Christoph Hübner, Bernhard Weschke, Jutta Gärtner: Mutations in the Gene Encoding Gap Junction Protein α12 (Connexin 46.6) Cause Pelizaeus-Merzbacher-Like Disease In: AJHG. 75, 2004, doi : 10.1086 / 422763 .
  12. ↑ Jutta Gärtner, Hugo Moser, David Valle: Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome. In: Nature Genetics. 1, 1992, p. 16, doi : 10.1038 / ng0492-16 .
  13. ↑ Jutta Gärtner has received an award for her research on rare congenital diseases. Retrieved May 23, 2020 .
  14. ^ Members. Retrieved March 24, 2020 .
personal data
SURNAME Gardener, Jutta
BRIEF DESCRIPTION German doctor and university professor
DATE OF BIRTH April 14, 1961
PLACE OF BIRTH Rheinhausen