Heidrun Potschka

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Heidrun Potschka (born May 14, 1968 in Hofheim am Taunus ) is a German veterinary pharmacologist and professor at the Ludwig Maximilians University in Munich .

Career

Potschka studied veterinary medicine at the Justus Liebig University in Giessen and received her doctorate there in 1997. She then moved to the University of Veterinary Medicine in Hanover and completed her habilitation there in 2004. From 2004 to 2006 she was a private lecturer and junior professor at the Institute for Pharmacology , Toxicology and Pharmacy .

Since 2006 she has been a professor at the Institute for Pharmacology, Toxicology and Pharmacy of the Veterinary Faculty of the Ludwig Maximilians University in Munich .

research

Potschka's research focus is epilepsy . She investigates the causes and therapies of epilepsy, especially in dogs, and researches the treatment of drug-resistant epilepsy. Their research results provide an important basis for the treatment of human epilepsy patients, since around a third of the patients do not respond to drug treatment ("drug-resistant epilepsy").

One focus of her is on multidrug transporter-mediated drug resistance. Potschka has identified an inadequate transport of active ingredients from the blood to the brain across the blood-brain barrier as one of the mechanisms for pharmacoresistance . Polymorphisms in the genes for these transport mechanisms (such as P-gylcoprotein or Pgp) can lead to a reduced concentration of active substances in the brain of these patients.

Awards

  • 2006 Falk Medical Research Trust Award
  • 2004 Prize of the Academy for Animal Health

Web links

Individual evidence

  1. Wolfgang Löscher, Heidrun Potschka: Role of Multidrug Transporters in Pharmacoresistance to Antiepileptic Drugs. In: Journal of Pharmacology and Experimental Therapeutics. 301, 2002, p. 7, doi : 10.1124 / jpet.301.1.7 .
  2. Wolfgang Löscher, Heidrun Potschka: Drug resistance in brain diseases and the role of drug efflux transporters. In: Nature Reviews Neuroscience. 6, 2005, p. 591, doi : 10.1038 / nrn1728 .
  3. ^ Members. Retrieved March 24, 2020 .
  4. ^ Michael Prize // International League Against Epilepsy. Retrieved May 25, 2020 .