Lentinan
| Structural formula | |||||||||
|---|---|---|---|---|---|---|---|---|---|
|
|||||||||
| General | |||||||||
| Surname | Lentinan | ||||||||
| other names |
LC-33 |
||||||||
| CAS number | 37339-90-5 | ||||||||
| Monomer | D -glucose | ||||||||
| Molecular formula of the repeating unit | C 6 H 10 O 5 | ||||||||
| Molar mass of the repeating unit | 162.14 g mol −1 | ||||||||
| PubChem | 37723 | ||||||||
| Type of polymer | |||||||||
| ATC code | |||||||||
| Brief description |
White dust |
||||||||
| Drug information | |||||||||
| Drug class | |||||||||
| properties | |||||||||
| Physical state |
firmly |
||||||||
| Melting point |
> 250 ° C (decomposition) |
||||||||
| solubility |
|
||||||||
| safety instructions | |||||||||
|
|||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||
Lentinan is a substance isolated from the Shiitake mushroom ( Lentinula edodes ).
From a chemical point of view, it is a glucan , with two β-1,6-glycosidic branches for every five straight-chain β-1,3- glycosidically linked monomers . The molecular weight of the polymers is between 400,000 and 800,000 Dalton .
Lentinan is said to have an immunomodulating and anti- neoplastic effect, there are few toxicological data. An infusion preparation containing lentinan for adjuvant cancer therapy has been marketed in Japan since 2000.
Individual evidence
- ↑ a b The Merck Index. An Encyclopaedia of Chemicals, Drugs and Biologicals. 13th edition, 2001, p. 5455.
- ↑ a b c d e Jürgen Falbe, Manfred Reglitz (ed.): RÖMPP Lexikon Chemie. Volume 3: H-L, 10th edition . Thieme, 1998, ISBN 3-13-735010-7 ( limited preview in Google book search).
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ Health risk from shiitake mushrooms. (PDF; 104 kB) BfR opinion of 23 June 2004.
- ^ Ajinomoto: History of Pharmaceuticals Business, October 2008. (PDF; 525 kB).
