Luigi Di Bella

Luigi Di Bella (born July 17, 1912 in Linguaglossa ; † July 1, 2003 in Modena ) was an Italian doctor and physiologist who became known in Italy and beyond due to controversial therapy recommendations for cancer. In 1997 and 1998, his therapy was the subject of much discussion, and his house was besieged for weeks by cancer patients and relatives seeking help. Conspiracy theories are also built around his views , stating that his therapy would be suppressed by scientific medicine in order not to endanger the spread of other therapies. These views are particularly popular in right-wing Italian circles and were promoted by the post-fascist national conservative party AN . Several organizations of followers (also called Dibelliani ) were formed in Italy who campaign for his therapy.

Di Bella's therapy recommendations are not recognized by modern medicine.

Life

Luigi Di Bella was born in Linguaglossa (Province of Catania ), studied medicine at the University of Bari and became a doctor in 1936. He subsequently became a lecturer in physiology at the University of Parma , later at the University of Modena . He retired in 1984, but then ran his own private research laboratory in which he also treated patients. In 2003 Di Bella died in Modena.

Di Bella's controversial therapy

Di Bella's treatment method is to be understood as a hormone therapy against cancer, which also includes vitamin supplements . The hormones somatostatin and melatonin are therefore able to cure cancer. Occasionally ACTH as well as cyclophosphamide and hydroxyurea were also integrated.

Di Bella's remedies are also sent from Switzerland to interested parties.

criticism

The illegal trade in somatostatin at high prices was under the control of mafia supporters for a time when Di Bella's therapy recommendations became public. Somatostatin was temporarily sold out and unavailable throughout Italy. A commission of inquiry set up by the Italian government and scientific studies came to the conclusion that the Di-Bella procedure in cancer is ineffective or has only a low effectiveness.

Melatonin is said to have a certain anti-cancer effect due to its action against free radicals, but the quantities required for this effect have serious consequences on sleep. A disorder of sexual development would be expected in childhood. Melatonin would have to be taken in high concentrations over many years in order to have a preventive effect. A curative effect is scientifically unknown.

literature

Di Bella L Ruolo del. Sistema abenulo-epifisario nella regolazione del tasso piastrinemico. Bol. SIBS, 1969, 45,
Di Bella L et al. Dinamica midollare dopo trattamento subacuto e cronico con Melatonina. Boll. SIBS, 1971, 47, Com. 125.
Di Bella L Orientamenti fisiologici nella terapia delle emopatie. Boll. Sc. Med. 1974, 1-3.
Di Bella L Physiological Basis for a rational therapy of bone marrow diseases. XVIth Internat. Congr. of Hematol., Kyoto, 1976, 9-45.
Di Bella L et al. Azione mielotropa della Melatonina (MLT). Boll. SIBS, 1976, 52, Com. 26.
Di Bella L et al. Effetti della somatostatina sulla funzione del midollo osseo. Boll. SIBS, 1977, 53, Com. 42.
Di Bella L et al. Perspectives in pineal functions. Progress in Brain Research, vol. 52, Elsevier Publ. Co., Amsterdam, 1979.
Di Bella L et al. L'aggregazione piastrinica in presenza di melatonina (MLT). Relazione alla Riunione della Società Italiana di Fisiologia, 25-26 Maggio 1979.
Di Bella L et al. Effetti della Melatonina (MLT) sulle piastrine in vitro. Boll. SIBS, 1979, 55, Com. 114.
Di Bella L et al. Sul ruolo fisiologico della Melatonina (MLT) nella regolazione del tasso piastrinemico, Boll. SIBS; 1979, 55, Com. 68.
Di Bella L et al. Melatonin: an essential factor for the treatment and recovery from leukemia and cancer. International Symposium on Melatonin, 1980, N.Birau & W.Schloot (Eds), p. 161-162.
Di Bella L et al. Platelet turnover as influenced by melatonin. International Symposium on Melatonin, 1980, N. Birau & W.Schloot (Eds.), P. 173-174.
Di Bella L et al. Red blood cells generation and melatonin. International Symposium on Melatonin, 1980, N.Birau & W.Schloot (Eds.), P. 175-176.
Di Bella L et al. Somatostatin in cancer therapy. 2nd International Symposium of Somatostatin, 1981.
Di Bella L et al. Neurotropic action of melatonin. Satellite Meeting of International Society for Neurochemistry, 1981.
Di Bella L et al. Molecular mechanism of bone marrow thrombocytogenesis by melatonin. Second Colloquium of the European Study Group, 1981.
Di Bella L et al. Bone marrow platelet production after melatonin iv infusion. Third colloquim of the European Pineal Study Group, Pécs, 1984.
Di Bella L et al. Some aspects of the neurothropic action of melatonin. Third colloquim of the European Pineal Study Group, Pécs, 1984.
Di Bella L et al. Melatonin in thrombocytogenesis. First International Congress on Melatonin in humans, Vienna, 7 September 1985.
Di Bella L et al. The bone marrow on the megacariocytes as a substrate of melatonin action. XXX Congress Proceedings of the International Union of Physiological Sciences, Vancouver, July 13th, 1986.
Di Bella L et al. 'Melatonin in Thrombocytogenesis', Intern. Workshop, Tubingen, Sept. 6-8, (1987), Rossi MT Published in The pineal Gland an Cancer Russel J. (Ed.), Reiter.
Di Bella L melatonin in cancer therapy. A satellite symposium of the 8th International Congress of Endocrinology, Hong Kong, Abstract from Symposium on melatonin and the pineal gland, 1988.
Di Bella L et al. Effect of Melatonin on circadian water intake by normal and tumor-bearing rats, Riunione cong. SIBS-SIF-SINU, Ischia, 1994.
Di Bella L Melatonina dalla ricerca agli interventi - Atti del convegno - Reggio Calabria 23/01/97
Di Bella L et al. Cytocalasin B influence on megacaryocyte patch-clamp. Congresso Internazionale di Amburgo, 27 August 1998.
Di Bella L et al. Melatonin effects on megakaryocyte membrane patch-clamp outward K + current. Med Sci Monit, 2002; 8 (12): BR527-531
Di Bella G., Colori B. Complete objective response of neuroblastoma to biological treatment. Neuro Endocrinol Lett.: 2009, 30 (4): 102-113. PO (PDF; 567 kB)
Di Bella G., Madarena M Complete objective response of oesophageal squamocellular carcinoma to biological treatment. Neuro Endocrinol Lett. 2009; 30 (3): 312-2 PO 1 (PDF; 531 kB)
Di Bella G., Complete objective response to biological therapy of plurifocal breast carcinoma, Neuro Endocrinol Lett. 2008, 29 (6): 857-66. PO (PDF; 5.4 MB)
Di Bella G. Il Metodo Di Bella. Mattioli Editore 3 ° Edizione 2005
Di Bella L, Gualano L. Key aspects of melatonin physiology: thirty years of research. Neuro Endocrinol Lett. 2006; 27 (4): 425-432.
Di Bella L, Rossi MT, Scalera G. Perspectives in pineal functions. Prog Brain Res. 1979; 52: 475-478.
Di Bella L. Orientamenti fisiologici nella terapia delle emopatie. Bull Sc Med. 1974; 145: 1-3
Di Bella L, Rossi MT, Scalera G. Perspectives in Pineal Function. Prog Brain Res. 1979; 52: 475-478
Proceedings of the Hanseatic Endocrine Conference on Melatonin after Four Decades an assessment of its potential, by James Olcese. ISBN 0-306-46134-X held August 27-30, Hamburg, Germany, 1998
L. Di Bella, L. Gualano, C. Bruschi, S. Minuscoli, and G. Tarozzi; CYTOCHALASIN B INFLUENCE ON MEGAKARIYOCYTE PATCH-CLAMP, Private Laboratory of Physiology-Via Marianini 45 Modena 1998.
Il multitrattamento Di Bella: risultati della sperimentazione (Ministero dalla Salute, 15/12/1999) (PDF; 173 kB)
Roberto Raschetti: Evaluation of an unconventional cancer treatment (the Di Bella multitherapy): results of phase II trials in Italy , British Medical Journal 1999; 318: 224-228
Di Bella L, Bruschi C, Gualano L. Melatonin effects on megakaryocyte membrane patch-clamp outward K + current. Med Sci Monit. 2002; 8 (12): 527-531
Di Bella L, Gualano L. Key Aspects of Melatonin Physiology: Thirty Years of Research. Neuro Endocrinol Lett. 2006; 27 (4): 425-432

Web links

personal data
SURNAME	Di Bella, Luigi
BRIEF DESCRIPTION	Italian doctor and physiologist
DATE OF BIRTH	July 17, 1912
PLACE OF BIRTH	Linguaglossa
DATE OF DEATH	July 1, 2003
Place of death	Modena