Mannosamine

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Structural formula
Mannosamine Structural Formulas V.1.svg
α- anomer (left) and β-anomer (right)
General
Surname Mannosamine
other names
  • 2-amino-2-deoxy- D- mannose
  • D- mannosamine
  • 2-amino-2-deoxymannose
Molecular formula
  • C 6 H 13 NO 5
  • C 6 H 13 NO 5 HCl (hydrochloride)
Brief description

colorless solid

External identifiers / databases
CAS number
PubChem 123961
ChemSpider 110483
Wikidata Q411775
properties
Molar mass 179.17 g mol −1
Physical state

firmly

Melting point

168 ° C (decomposition, hydrochloride )

solubility

soluble in water (hydrochloride)

safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Mannosamine is a hexosamine derivative of mannose .

In its N -acetyl form ( N -acetyl- D -mannosamine) it is a component of neuraminic acids , glycolipids and glycoproteins . D -Mannosamine hydrochloride is a monosaccharide starting material for a number of biologically functional derivatives . It is used for the synthesis of N -propanoylmannosamine and sialic acids and is also an intermediate for a number of biologically active compounds and pharmaceuticals that are derived from carbohydrates .

Individual evidence

  1. ↑ a b M. P. Lisanti et al., "Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins", The EMBO Journal 10, No. 8 (August 1991): 1969-1977 ( PMID 1829673 ).
  2. ↑ a b Data sheet D-Mannosamine hydrochloride from Sigma-Aldrich , accessed on January 29, 2012 ( PDF ).
  3. ^ A b New Zealand Pharmaceuticals: D-Mannosamine hydrochloride
  4. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.