Matthias Endres

from Wikipedia, the free encyclopedia

Matthias Endres (born April 7, 1969 in Sigmaringen ) is a German neurologist and stroke researcher at the Berlin Charité .

Life

Endres studied medicine at the Ruhr University Bochum and the University of Hamburg from 1988 to 1994 (from 1991 with the support of the German National Academic Foundation ) . In 1995 he received his doctorate from the University of Hamburg with the thesis Molecular genetic characterization of the pathogenicity factors of Staphylococcus epidermidis , in 1996 he received his license to practice medicine and passed the United States Medical Licensing Examination . After working as an assistant doctor in neurology at the University of Lübeck , he went to the Massachusetts General Hospital of Harvard Medical School in Boston as a postdoctoral fellow with Michael Moskowitz . From 1998 Endres worked as an assistant doctor to Karl Max Einhäupl at the Berlin Charité . Here he completed his habilitation in 2001 with the work cytoskeleton as a target for stroke therapy . In 2002 he acquired the field title ( specialist ) in neurology. From 2003 Endres had a Heisenberg grant from the German Research Foundation at the Charité , and from 2005 a Lichtenberg professorship from the Volkswagen Foundation .

Endres received a W3 professorship at the Charité in 2008 and took over the management of the Clinic for Neurology there and the Center for Stroke Research Berlin (CSB) . Today (as of 2018) he is Director of the Clinic for Neurology and Medical Director of the Charité Center 15 for Neurology, Neurosurgery and Psychiatry .

On July 13, 2016, Matthias Endres was elected a member ( matriculation number 7706 ) of the Leopoldina .

Act

Endres' working group is primarily concerned with stroke research. Particular attention is paid to the factors that have a preventive effect ( endothelial function , physical activity, influence of medication), the mechanisms of cell death (activation of the cell cycle , DNA damage and repair , apoptosis ), neurological regeneration and outcome ( neuronal plasticity , neurogenesis ) and clinical studies on stroke units and telemedicine .

Awards (selection)

  • 1998: Oskar Lapp Research Award from the German Society for Cardiology
  • 2002: Adolf Wallenberg Prize of the German Society for Neurology
  • 2002: Paul Martini Prize for the work Neuroprotection mediated by changes in the endothelial actin cytoskeleton , Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription and Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice .
  • 2008: Heinrich Pette Prize of the German Society for Neurology

literature

  • Leopoldina Newly Elected Members 2016, Leopoldina, Halle (Saale) 2017, p. 11 ( PDF )

Web links

  • CV (as of 2005, English; PDF; 206 kB) at neuroscience-berlin.de
  • CV (as of 2011, English; PDF; 906 kB) at neurocure.de

Individual evidence

  1. ↑ Cytoskeleton as a target for stroke therapy. Habilitation thesis to obtain a teaching qualification for the subject of experimental neurology. Document server of the Humboldt University of Berlin (hu-berlin.de); Retrieved June 30, 2013
  2. ↑ Member entry by Prof. Dr. Matthias Endres (with picture and CV) at the Deutsche Akademie der Naturforscher Leopoldina , accessed on January 5, 2017.
  3. ↑ Oskar Lapp Research Award at the German Cardiac Society (dgk.org); Retrieved June 30, 2013
  4. ^ Awards of the DGN: Adolf Wallenberg Prize at the German Society for Neurology (dgn.org); Retrieved June 30, 2013
  5. ^ Winner of the Paul Martini Prize since 1969 with the Paul Martini Foundation (paul-martini-stiftung.de); Retrieved June 30, 2013
  6. ↑ U. Laufs, M. Endres, N. Stagliano, S. Amin-Hanjani, DS Chui, SX Yang, T. Simoncini, M. Yamada, E. Rabkin, PG Allen, PL Huang, M. Böhm, FJ Schoen, MA Moskowitz, JK Liao: Neuroprotection mediated by changes in the endothelial actin cytoskeleton. In: The Journal of clinical investigation. Volume 106, Number 1, July 2000, pp. 15-24, ISSN  0021-9738 . doi: 10.1172 / JCI9639 . PMID 10880044 . PMC 314365 (free full text).
  7. ↑ U. Laufs, M. Endres, F. Custodis, K. Gertz, G. Nickenig, JK Liao, M. Böhm: Suppression of endothelial nitric oxide production after withdrawal of statin treatment is mediated by negative feedback regulation of rho GTPase gene transcription . In: Circulation . Volume 102, Number 25, December 2000, pp. 3104-3110, ISSN  1524-4539 . PMID 11120702 .
  8. ↑ U. Laufs, K. Gertz, P. Huang, G. Nickenig, M. Böhm, U. Dirnagl, M. Endres: Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice. In: Stroke . Volume 31, Number 10, October 2000, pp. 2442-2449, ISSN  1524-4628 . PMID 11022078 .
  9. ^ Awards of the DGN: Heinrich Pette Prize at the German Society for Neurology (dgn.org); Retrieved June 30, 2013
personal data
SURNAME Endres, Matthias
BRIEF DESCRIPTION German neurologist
DATE OF BIRTH April 7, 1969
PLACE OF BIRTH Sigmaringen