Michael Grunstein

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Michael Grunstein (* 1946 in Romania ) is a Romanian -American biochemist and professor at the University of California in Los Angeles , California (UCLA).

Life

Grunstein earned a bachelor's degree from McGill University in Montreal , Canada and a Ph.D. at the University of Edinburgh in the UK . He worked as a postdoctoral fellow at Stanford University in Stanford , California . In 1975 he went to the University of California in Los Angeles , California (UCLA).

Act

Grunstein invented the colony hybridization screening technique of recombinant DNAs as a postdoctoral fellow in David Hogness' laboratory . At UCLA he did fundamental work on the genetic analysis of histones in yeasts . He was able to show for the first time that histones regulate gene activity . His achievements include the evidence that histones and histone acetylation the transcription regulate and the deciphering of the histone code .

Awards (selection)

literature

  • Jenny Ruth Morber: Profile of Michael Grunstein. In: Proceedings of the National Academy of Sciences. Volume 108, No. 46, 2011, pp. 18597-18599, doi: 10.1073 / pnas.1116909108

Web links

Individual evidence

  1. Book of Members 1780 – present, Chapter G. (PDF; 931 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 1, 2019 .
  2. Massry Prize Winners (1996 – Present) at usc.edu; accessed on May 1, 2019.
  3. ^ Past Winners - Rosenstiel Award - Rosenstiel Basic Medical Sciences Research Center - Brandeis University. In: brandeis.edu. Retrieved January 23, 2016 .