Nasal ointment
A nasal ointment is a semi-solid preparation for application to the mucous membrane of the nose , usually to achieve a local effect. They are usually presented in tubes that are equipped with a nasal applicator . A distinction is made between preparations for multiple and single use.
Nasal ointments with a medicinal effect are drugs , those with a physiological or physical effect are medical products . In addition to ready-made preparations, there are also individual recipes .
properties
Nasal ointments consist of an ointment base that can contain active pharmaceutical ingredients. Ointment bases for nasal ointments are based on paraffinic and fatty lipids. Water-absorptive bases are frequently using wool alcohol ointment, lanolin, lanolin or an emulsifier to Diglycerolester base (z. B. Softisan 649 ) was prepared. In addition to nasal ointments as semi-solid preparations also are hydrophobic nasal creams and hydrophilic Nasengele applied. Hydrophilic creams are unsuitable as preparations for the nose. If the ciliated epithelium is intact, hydrophilic nasal gels meet the physiological requirements more than lipid-containing preparations.
Nasal ointments must be soft enough to spread well on the mucous membrane, on the other hand firm enough to prevent aspiration with the risk of lipid pneumonia . Hydrophobic nasal ointments or creams are only displayed in certain cases, inter alia, rhinitis sicca anterior , atrophic rhinitis and Ozaena .
Medicinal substances typically used in nasal ointments are, for example, mupirocin , epinephrine , dexamethasone , menthol or dexpanthenol .
Recipe examples
Tübingen nasal ointment
The Tübingen nasal ointment is a yellow ointment of sage oil , hydrocortisone , xylometazoline , vitamin A - palmitate , dexpanthenol ointment and olive oil . It is used for post-surgical care after nose operations and is intended to support the healing process after surgical interventions on the nose.
The ointment requires a prescription.
Nasal ointment containing chlorhexidine
The chlorhexidine-containing nasal ointment (formerly known as " Bremer Nasensalbe ") is a yellow ointment made from chlorhexidine diacetate , propylene glycol , medium-chain triglycerides and wool wax . Optionally, it can contain mint oil .
The ointment does not require a prescription.
This ointment is used against injured mucous membranes after invasive surgical interventions (e.g. nasal surgery on the septum , sinuses , nasal concha , etc.), which often result in restricted blood flow and, in addition, insufficient moisture (humidification of the air) prevents dehydration and irritation of the mucous membranes.
literature
- Rudolf Voigt: Pharmaceutical Technology . 11th edition, 2010, Deutscher Apotheker Verlag, ISBN 978-376-925003-9 . P. 403 ff.
- DAC / NRF plant , as of September 2019.
- Recipe information: nasal ointments and nasal emulsions . ( Memento of September 27, 2007 in the Internet Archive ) (PDF; 42 kB) New recipe form, November 28, 2006.
Web links
- Between plausibility and popularity - a well-tried nasal ointment recipe (article in the DAZ by Cornelia Bruns, July 23, 2015)