Nonivamide

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Structural formula
Structural formula of nonivamide
General
Non-proprietary name Nonivamide
other names
  • N - (4-Hydroxy-3-methoxybenzyl) nonanamide ( IUPAC )
  • Pseudocapsaicin
  • Pelargonic acid vanillylamide (PAVA)
Molecular formula C 17 H 27 NO 3
External identifiers / databases
CAS number 2444-46-4
EC number 219-484-1
ECHA InfoCard 100.017.713
PubChem 2998
ChemSpider 2891
DrugBank DB11324
Wikidata Q420228
Drug information
ATC code

M02 AB03

Drug class

Rubefacience

properties
Molar mass 293.40 g mol −1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 315-317-319-335
P: 261-280-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Nonivamide or pseudocapsaicin is a synthetic capsaicin that is used as a drug or irritant .

Chemical properties

Chemically, nonivamide differs from capsaicin in that it lacks a double bond and a methyl group in the side chain.

use

Nonivamide acts as an analgesic and stimulates blood flow and is therefore used for rheumatic muscle, joint and nerve pain .

Pseudocapsaicin is also used as an active ingredient in pepper spray or in pepper gas cartridges for alarm guns .

pharmacology

Nonivamide is a synthetic capsaicin analog with analgesic properties, which leads to a reduction in substance P in the peripheral pain-sensitive C fibers and Aδ nerve fibers when repeatedly applied to the skin.

Trade names

Monopreparations
  • Gothaplast Capsi-med warming plaster (D)
  • ABC warming plaster (D)
Combination preparations
  • Finalgon (D, A), Histalgan (CH), Rubriment (A, CH)

Individual evidence

  1. ↑ a b Data sheet N-Vanillylnonanamide from Sigma-Aldrich , accessed on April 16, 2011 ( PDF ).

Web links