Paul Kallós

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Paul Kallós (* 1902 in Budapest ; † March 13, 1988 ) was a Swedish immunologist and allergist .

Kallos studied medicine at the Royal Elisabeth University in Pest and later emigrated to Germany (Leipzig, Nuremberg). There he married the physician Elisabeth Deffner in 1932, with whom he later worked. In 1932 both went to Switzerland and in 1934 to Sweden. There Kallos worked as an immunologist in the hospital of Uppsala University and from 1937 at the Wenner Gren Institute in Stockholm . From 1944 he and his wife had their own laboratory in Helsingborg (Wihlborg Labor).

He first studied immune reactions, especially via macrophages , in tuberculosis infection. He later studied asthma in guinea pigs under controlled laboratory conditions. For example, he examined the contraction of the uteri of guinea pigs as a measure of irritation from allergens . He found that this did not depend on the molar mass of the allergens, which indicated that the allergens interacted with the antibodies only via the surface and that it was independent of diffusion mechanisms.

In addition, he researched hypersensitivity ( idiosyncrasy ) to drugs such as ASA that were not triggered by immune reactions and developed the concept of pseudoallergic reactions with G. West, HD Schlumberger and P. Dukor .

He was editor of the International Archives of Allergy and Applied Immunology and the monograph series Progress in Allergy and Monograph in Allergy , and in 1954 co-founder and first secretary of the Collegium Internationale Allergologicum (CIA).

In 1974 he received the Robert Koch Medal . He received the Karl Hansen Medal of the German Society for Allergy and Clinical Immunology, the Pirquet Gold Medal and was an honorary doctor from Lund and Göteborg.

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