Pentaacetyl-α- D -glucose

Structural formula
General
Surname	Pentaacetyl-α- D -glucose
other names	1,2,3,4,6- penta- O- acetyl-α- D -glucopyranose
Molecular formula	C 16 H 22 O 11
External identifiers / databases
CAS number 604-68-2 EC number 210-073-2 ECHA InfoCard 100.009.158 PubChem 2723636 Wikidata Q27252242
properties
Molar mass	390.34 g mol −1
Melting point	109-111 ° C
Refractive index	≥ + 98 ° (c = 1 in ethanol)
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

Pentaacetyl-α- D -glucose (also α- D - (+) - glucose pentaacetate ) is a chemical compound from the group of monosaccharides . It is produced from anhydrous α- D - (+) - glucose in acetic anhydride in the presence of zinc chloride . On the human tongue, α- D - (+) - glucose pentaacetate produces a bitter taste . α- D - (+) - glucose pentaacetate increases the secretion of insulin in beta cells .

literature

• WJ Malaisse: Insulin release: the receptor hypothesis. In: Diabetologia . Volume 57, Number 7, July 2014, pp. 1287-1290, doi: 10.1007 / s00125-014-3221-0 . PMID 24700279 .

Individual evidence

1. ↑ ^{a b c} Data sheet α-D (+) - Glucose pentaacetate, 99% from Sigma-Aldrich , accessed on July 4, 2019 ( PDF ).
2. ^ Addison Ault: Techniques and Experiments For Organic Chemistry. 1998, ISBN 0-935702-76-8 , p. 433.
3. ↑ ^{a b} Itaru Kojima: Glucose-sensing Receptor in Pancreatic Beta-Cells. 2018, ISBN 978-981-1300-01-1 , p. 14.