Peter Pflegel

from Wikipedia, the free encyclopedia

Klaus Peter Pflegel (* 1936 in Königsberg (East Prussia) ; † 2017 ) was a German pharmacist and pharmacist . His main topic was biopharmacy , a field in which he published and in which he taught as a professor at the Ernst-Moritz-Arndt University of Greifswald in Greifswald . From 1994 to 1996 he was Dean of the Faculty of Mathematics and Natural Sciences in Greifswald. For many years he was editor-in-chief of the trade journal Die Pharmazie .

life and work

Pflegel was born in Königsberg (East Prussia) in 1936 . Shortly before the end of the Second World War, his mother fled west with him. He completed his school education in Moritzburg and later studied pharmacy in Leipzig.

After completing his studies, Pflegel did research in Leipzig. Among other things, he worked as a research assistant for Hans Beyer and Roland Pohloudek-Fabini . Initially he devoted himself to pharmacology in the animal body, but soon the polarographic reduction of quinoxalones , which he described for the first time in 1968. Funded by Pohloudek, he was in Berlin and Leipzig from 1968 to 1976, where he carried out pharmacological studies on the absorption of benzodiazinone and fruit extracts in the body and gained some basic knowledge about the microbiological determination of the value. After his return he received a teaching position in Greifswald in 1976.

In research and teaching, he was a strict advocate of quantitative key figure analysis, which derives its laboratory values ​​primarily from the microbiological value determination he has refined in reduction and cleavage processes. Several pharmacological analysis methods that have so far yielded a purely binary result (yes / no) have been able to provide quantifiable results as a result of Pflegeel's research. Particularly noteworthy are his basic work with the Magdeburg pharmacologist Manfred Falk in the 1980s on artificial lipoid membranes, with which the interactions of various active ingredients could be quantified.

In 1984, together with Siegfried Pfeifer and Hans-Hubert Borchert, he founded the standard work Basics of Biopharmacy (later Pharmaceutical Technology / Biopharmacy ). The analysis of the absorption of grapefruit seed extract into the human organism belongs to his last research areas. He retired in 2001 and lived near Greifswald. Pflegel was among other things the holder of the Döbereiner Medal of the Pharmaceutical Society of the GDR and an honorary doctorate from the Medical University of Szeged.

Fonts

  • Contributions to the mechanism of the fermentation breakdown of bis-glycosides , Leipzig 1963
  • with C. Meinecke and H. Richter: Pharmaceutical Guide for Veterinarians and Students of Veterinary Medicine , Leipzig 1967
  • with G. Wagner: Polarographic reduction of quinoxalones , Berlin 1968
  • Contributions to the polarography of benzodiazinones and the polarographic determination of medicinal products of the quinazolone, quinoxalone and phthalazone series , Leipzig 1969
  • with K. Schmidt and G. Wagner: About the mode of action of bezodiazepam , Leipzig 1973
  • Practice of microbiological value determination in pharmacology , Leipzig 1975
  • with S. Pfeifer and H.-H. Borchert: Fundamentals of biopharmacy: pharmacokinetics, bioavailability, biotransformation , Berlin 1984
  • Pharmacokinetics , Berlin 1991
  • Biopharmacy and Pharmaceutical Technology , Berlin 1994

Web links

Individual evidence

  1. Prof. Dr. Peter Pflegel: Obituary notice , Ostsee-Zeitung from February 7, 2017.
  2. http://www.pharmazeutische-zeitung.de/index.php?id=pharm4_06_1999
  3. ^ Separated: Personnel reports from Greifswald from September 27, 2001