Pinacol
| Structural formula | |||||||||||||||||||
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| General | |||||||||||||||||||
| Surname | Pinacol | ||||||||||||||||||
| other names |
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| Molecular formula | C 6 H 14 O 2 | ||||||||||||||||||
| Brief description |
colorless tablets |
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| properties | |||||||||||||||||||
| Molar mass | 118.17 g mol −1 | ||||||||||||||||||
| Physical state |
firmly |
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| density |
0.97 g cm −3 |
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| Melting point |
38 ° C |
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| boiling point |
174 ° C |
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| solubility |
Slightly soluble in cold, good in hot water, diethyl ether and ethanol |
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| safety instructions | |||||||||||||||||||
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| MAK |
3380 mg kg −1 (mouse, oral) |
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||||||||
Pinacol (from the Greek pinákion , ' little tablet'), formerly also called pinacon , is an organic compound from the group of alkanediols . The two hydroxyl groups are in the pinacol on adjacent carbon atoms (in a vicinal position ). Pinacols can be produced from ketones or aldehydes by a pinacol coupling reaction, with radical anions occurring as intermediates.
Pinacole
Starting from the pinacol, compounds with the structure R 1 R 2 C (OH) C (OH) R 3 R 4 (with the radicals R 1 - R 4 , where the two OH groups are on adjacent carbon atoms) are generally referred to as pinacols ( substituted 1,2- diols ). Pinacols can undergo acid-catalyzed pinacol rearrangements to pinacolones.
Examples of derived connections:
use
Pinacol is used as:
- Intermediate product for the manufacture of pharmaceuticals (e.g. 2-aminophenylboronic acid pinacol ester)
- Intermediate product for the production of pinacolone
Individual evidence
- ↑ a b Entry on Pinacol. In: Römpp Online . Georg Thieme Verlag, accessed on June 7, 2014.
- ↑ Pinakol data sheet (PDF) from Merck , accessed on January 19, 2011.
- ↑ a b c d data sheet Pinacol from Sigma-Aldrich , accessed on April 20, 2011 ( PDF ).
- ↑ Entry on Pinakol at ChemBlink , accessed on February 25, 2011.
- ↑ thegoodscentscompany.com: Data sheet Pinacol 76-09-5
- ↑ chemicalland21.com: PINACOL (TETRAMETHYLETHYLENE GLYCOL) .
- ↑ External identifiers or database links for 1,2,2-trimethylpropyldimethylphosphinate : CAS number: 92411-69-3, PubChem : 119152 , ChemSpider : 106451 , Wikidata : Q82891657 .
- ↑ External identifiers of or database links to hexafluoro-2,3-bis (trifluoromethyl) -2,3-butanediol : CAS number: 918-21-8, EC number: 624-621-7, ECHA InfoCard : 100.153.195 , PubChem : 13518 , ChemSpider : 12930 , Wikidata : Q72481695 .
