Pyrisoxazole

Structural formula
Diastereomer mixture - (3 R , 5 R ) -isomer (top) and (3 R , 5 S ) -isomer (bottom)
General
Surname	Pyrisoxazole
other names	3 - [(3 R , 5 RS ) -5- (4-chlorophenyl) -2,3-dimethyl-3-isoxazolidinyl] pyridine
Molecular formula	C 16 H 17 ClN 2 O
External identifiers / databases
CAS number 847749-37-5 [(3 R , 5 R ) and (3 R , 5 S ) isomer mixture] 291771-99-8 [(3 R , 5 R ) -isomer] 291771-83-0 [(3 R , 5 S ) -isomer] PubChem 71300861 Wikidata Q27157258
properties
Molar mass	288.77 g mol −1
Physical state	firmly
safety instructions
GHS hazard labeling no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Chemically, pyrisoxazole belongs to the group of pyridines and oxazoles . It is a fungicide and belongs to the group of active substances called Conazoles , which inhibit C14 demethylase in sterol synthesis.

Pyrisoxazole was developed in China by the research institute SYRICI and is used as a mixture of diastereomers consisting of the (3 R , 5 R ) and the (3 R , 5 S ) isomers .

Pyrisoxazole has high activity against Ascomycota and Basidiomycetes . It is already approved in China to combat gray mold rot ( Botrytis cinerea ) in tomato cultivation. In the European Union and in Switzerland it is not approved as a crop protection agent.

Individual evidence

1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
2. ^ Entry by Alan Wood.
3. ↑ Fengping Chen, Ping Han, Pengfei Liu, Naiguo Si, Junli Liu, Xili Liu: Activity of the novel fungicide SYP-Z048 against plant pathogens . In: Scientific Reports . tape 4 , September 25, 2014, p. 6473 , doi : 10.1038 / srep06473 ( PDF ).
4. ^ Directorate-General for Health and Food Safety of the European Commission: EU pesticide database ; Entry in the national directory of plant protection products in Switzerland ; Retrieved June 26, 2016.