Rudiger Klein

Rüdiger Klein (born March 24, 1958 in Nickenich ) is director of the “Molecules - Signals - Development” department at the Max Planck Institute for Neurobiology .

Live and act

Klein studied biology at the universities of Marburg and Tübingen and at Juniata College (USA). He received his doctorate from the University of Tübingen. As a postdoctoral fellow, he worked at the Frederick Cancer Research and Development Center (USA) and the Bristol-Myers Squibb Pharmaceutical Research Institute (USA). He then headed a junior research group at the European Molecular Biology Laboratory (EMBL) in Heidelberg before he was appointed scientific member and director at the Max Planck Institute for Neurobiology in 2001 .

Rüdiger Klein's work deals with the molecular mechanisms that enable the exchange of information between nerve cells.

As a young scientist, Rüdiger Klein succeeded in discovering the receptors (TRK) of certain nerve growth factors (NGF). (Klein et al., Cell 1991a, b) He also provided evidence that certain messenger substances ( ephrins ) direct the axons of nerve cells through rejection. (Henkemeyer et al., Cell 1996; Orioli et al., EMBO Journal 1996; Brückner et al., Science 1997) He made the discovery that Ephrins regulate not only the development of the nervous system , but also the lymphatic vessels and blood vessels . (Adams et al., Genes Dev. 1999; Mäkinen et al. Genes Dev. 2005)

In 2005 he received the Hansen Family Prize .

Web links

• Homepage of the Molecules - Signals - Development department