Ribulose-5-phosphate
Structural formula | ||||||||||
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D- ribulose-5-phosphate | ||||||||||
General | ||||||||||
Surname | Ribulose-5-phosphate | |||||||||
other names |
Ribulose-5P |
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Molecular formula | C 5 H 11 O 8 P | |||||||||
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properties | ||||||||||
Molar mass | 230.11 g mol −1 | |||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
D - ribulose-5-phosphate is the form of D - ribulose that is phosphorylated on the C5 carbon atom and plays a central role in numerous metabolic steps.
Biological importance
education
Ribulose-5-phosphate is formed from 6-phosphogluconate , catalyzed by 6-phosphogluconate dehydrogenase . Here, 6-phosphogluconate is decarboxylated via an intermediate stage and NADP + is reduced.
This is one of the first steps in the pentose phosphate route or the phosphoketolase route in heterofermentative lactic acid fermentation . The reaction itself is involved in a great many metabolic pathways, such as in the Calvin cycle or in the ribulose monophosphate pathway .
use
In the pentose phosphate pathway, a ribose-5-phosphate isomerase catalyzes the conversion of ribulose-5-phosphate to ribose-5-phosphate and a ribulose-phosphate-3-epimerase catalyzes the conversion to xylulose-5-phosphate .
In the Calvin cycle, ribulose-5-phosphate is converted into a diphosphorylated form, D - ribulose-1,5-bisphosphate, through ATP consumption .
It is also used as a basic building block in the biosynthesis of isoalloxazine and pteridine .
literature
- Albert L. Lehninger, David L. Nelson, Michael M. Cox: Principles of Biochemistry . 2nd Edition. Spektrum, Heidelberg, Berlin, Oxford 1994, ISBN 3-86025-106-6 , pp. 509, 719 .
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.