Ribulose-5-phosphate

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Structural formula
Structural formula of ribulose-5-phosphate
D- ribulose-5-phosphate
General
Surname Ribulose-5-phosphate
other names

Ribulose-5P

Molecular formula C 5 H 11 O 8 P
External identifiers / databases
CAS number
  • 4151-19-3
  • 2922-69-2 ( L -isomer)
  • 551-85-9 ( D isomer)
PubChem 439184
Wikidata Q418886
properties
Molar mass 230.11 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

D - ribulose-5-phosphate is the form of D - ribulose that is phosphorylated on the C5 carbon atom and plays a central role in numerous metabolic steps.

Biological importance

education

Ribulose-5-phosphate is formed from 6-phosphogluconate , catalyzed by 6-phosphogluconate dehydrogenase . Here, 6-phosphogluconate is decarboxylated via an intermediate stage and NADP + is reduced.

This is one of the first steps in the pentose phosphate route or the phosphoketolase route in heterofermentative lactic acid fermentation . The reaction itself is involved in a great many metabolic pathways, such as in the Calvin cycle or in the ribulose monophosphate pathway .

use

In the pentose phosphate pathway, a ribose-5-phosphate isomerase catalyzes the conversion of ribulose-5-phosphate to ribose-5-phosphate and a ribulose-phosphate-3-epimerase catalyzes the conversion to xylulose-5-phosphate .

In the Calvin cycle, ribulose-5-phosphate is converted into a diphosphorylated form, D - ribulose-1,5-bisphosphate, through ATP consumption .

It is also used as a basic building block in the biosynthesis of isoalloxazine and pteridine .

literature

  • Albert L. Lehninger, David L. Nelson, Michael M. Cox: Principles of Biochemistry . 2nd Edition. Spektrum, Heidelberg, Berlin, Oxford 1994, ISBN 3-86025-106-6 , pp. 509, 719 .

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

Web links

Wikibooks: Biochemistry and Pathobiochemistry: Hexose Monophosphate Pathway  - Learning and Teaching Materials