Silver salicylate

Structural formula
General
Surname	Silver salicylate
Molecular formula	C 7 H 5 AgO 3
Brief description	white solid; white odorless solid (hydrate);
External identifiers / databases
PubChem	54683737
Wikidata	Q50666929
properties
Molar mass	244.99 g mol −1
Physical state	firmly
solubility	poorly soluble in water (0.95 g / l at 23 ° C, hydrate); insoluble in ethanol , ethyl acetate , ether , tetrahydrofuran and benzene ; soluble in 2-methylthioethanol ;
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 315-319-335
	P: 261-280-305 + 351 + 338-304 + 340-405-501
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Silver salicylate is a chemical compound of silver from the group of salicylates .

Extraction and presentation

Silver salicylate can be obtained by reacting a solution of salicylic acid in ethanol with silver nitrate at 60-70 ° C.

properties

Silver salicylate is a white solid which, as a hydrate, is sparingly soluble in water.

use

Silver salicylate can be used as an intermediate in the manufacture of drugs. It also serves as a catalyst for the classic Koenigs-Knorr reaction , as an accelerator for the heavy metal-assisted cleavage of thiazolidine rings and in the nucleophilic displacement of alkyl iodides .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f Nycholat, CM and Lowary, TL: Silver Salicylate . In: e-EROS Encyclopedia of Reagents for Organic Synthesis . 2005, doi : 10.1002 / 047084289X.rn00545 .
↑ ^a ^b ^c ^d ^e ^f ^g Data sheet Silver salicylate hydrate from AlfaAesar, accessed on March 17, 2018 ( PDF )(JavaScript required) .
↑ Franz v. Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe: Hager's Handbook of Pharmaceutical Practice, Volume 5: Substances LZ . Springer-Verlag, 2013, ISBN 978-3-642-58388-9 , pp. 222 ( limited preview in Google Book search).

[10.1002/047084289X.rn00545-1] ↑ ^a ^b ^c ^d ^e ^f Nycholat, CM and Lowary, TL: Silver Salicylate . In: e-EROS Encyclopedia of Reagents for Organic Synthesis . 2005, doi : 10.1002 / 047084289X.rn00545 .

[Alfa-2] ↑ ^a ^b ^c ^d ^e ^f ^g Data sheet Silver salicylate hydrate from AlfaAesar, accessed on March 17, 2018 ( PDF )(JavaScript required) .

[Franz_v._Bruchhausen,_Siegfried_Ebel,_Eberhard_Hackenthal,_Ulrike_Holzgrabe-3] Franz v. Bruchhausen, Siegfried Ebel, Eberhard Hackenthal, Ulrike Holzgrabe: Hager's Handbook of Pharmaceutical Practice, Volume 5: Substances LZ . Springer-Verlag, 2013, ISBN 978-3-642-58388-9 , pp. 222 ( limited preview in Google Book search).