Stefan dowel

from Wikipedia, the free encyclopedia

Stefan Dübel (born January 13, 1960 in Hanau , Hessen ) is a German biologist . Since October 2002 he has been a professor at the Technical University of Braunschweig and head of the biotechnology department of the Institute for Biochemistry, Biotechnology and Bioinformatics.

education and profession

Stefan Dübel studied biology from 1978 to 1983 at the Johannes Gutenberg University in Mainz and at the Ruprecht Karls University in Heidelberg . He then completed his community service . From 1986 to 1989 he did his doctorate at the Center for Molecular Biology at Heidelberg University. He was then a postdoc at the German Cancer Research Center , where, together with Frank Breitling, he made a significant contribution to the development of the antibody phage display and human and synthetic antibody gene libraries for the production of human antibodies, as well as at the Institute for Cell Biology and Immunology at the University of Stuttgart . From 1996 to 2001 he was group leader at the Department of Molecular Genetics at the University of Heidelberg , where he completed his habilitation in 1997 with Ekkehard Bautz . From 2001 to 2002 he was CSO of LifeBits AG. Since October 2002 he has been a professor at the Technical University of Braunschweig . He is the co-founder of several biotech companies, including a. a company for the animal-free production of antibodies (Abcalis) and the YUMAB. Together with Frank Breitling, he is the author of the first German-language textbook on recombinant antibodies and, together with Janice Reichert, editor of the multi-volume Handbook of therapeutic antibodies . Together with Michael Hust and Gundram Jung, he initiated the Corona Antibody team ( CORAT ), which develops neutralizing human antibodies for the treatment of COVID-19 , and from which CORAT Therapeutics GmbH emerged with the support of the State of Lower Saxony .

Research work

Recombinant antibodies , antibodies , phage display , proteome research, therapeutic antibodies.

Awards

  • 2013 Entrepreneurship Award from TU Braunschweig and Ostfalia
  • 2014 LehrLEO Prize for good teaching from the TU Braunschweig
  • 2015 Innovation in Biotechnology Award from the American Association of Pharmaceutical Scientists (AAPS)
  • 2016 Technology Transfer Prize from the Braunschweig Chamber of Commerce
  • 2017 1st prize from the Lower Saxony innovation network
  • 2018 winner of the Go-BIO competition (with the NordenVaccines team) [Link to BMBF]
  • 2019 Innovation Award of the BioRegions of Germany (with the NordenVaccines team) [Link to press release]

Web links

Individual evidence

  1. ↑ Patent: Production and use of gene banks for synthetic human antibodies ("synthetic human anti-body libraries) . November 20, 1996 ( dpma.de [accessed on August 1, 2016]).
  2. ↑ Patent: Phagemid for screening antibodies . March 21, 2001 ( dpma.de [accessed August 1, 2016]).
  3. ↑ Start-up for sustainable antibody production - spin-off from TU Braunschweig is working on broad application. Technical University of Braunschweig , December 10, 2019, accessed on January 24, 2020 (Abcalis spin-off).
  4. ^ Animal Use Statement. Abcalis, accessed January 24, 2020 .
  5. ↑ People. YUMAB, accessed on January 24, 2020 (English, including information on founding).
  6. ↑ F. Breitling, S. dowel: Recombinant antibodies . Spektrum Akad. Verlag, Heidelberg 1997 (latest edition 2019: ISBN 978-3-662-50275-4 , online )
  7. ↑ Stefan Dübel, Janice M. Reichert (Ed.): Handbook of Therapeutic Antibodies . 2nd Edition. Wiley-Blackwell, 2014, ISBN 978-3-527-32937-3 (English).
  8. ↑ https://www.tu-braunschweig.de/fileadmin/Redaktionsgruppen/Institute_Fakultaet_2/BBT-Biotech/PDFs/Pressemeldung_Land_beteiligt_sich_an_Braunschweiger_Pharmaentwickler.pdf
  9. ↑ Entrepreneurship Award for Prof. Stefan Dübel and for StudING
  10. ↑ Laureates of the LehrLEO 2014 ( Memento from July 4, 2015 in the Internet Archive )
  11. ^ Past Award Recipients - AAPS Historical Awards. (PDF) American Association of Pharmaceutical Scientists (AAPS) , p. 7 , accessed on January 24, 2020 (English, under Innovation in Biotechnolgy Award ). Available at AAPS Awards. AAPS, accessed January 24, 2020 .
  12. ↑ The winners. IHK Braunschweig , accessed on January 24, 2020 (winner of the technology transfer award 2016).
  13. ↑ Prize of the Innovation Network 2017. Innovationsnetzwerk Niedersachsen, accessed on January 24, 2020 .
personal data
SURNAME Dowel, Stefan
BRIEF DESCRIPTION German biologist and biotechnologist
DATE OF BIRTH January 13, 1960
PLACE OF BIRTH Hanau , Hesse