Steven McKnight

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Steven Lanier McKnight (* 1949 ) is an American biochemist and molecular biologist . He is best known for his work on the systems that cells and tissues use to respond to a critical supply of oxygen.

Live and act

McKnight earned a bachelor's degree in biology from the University of Texas at Austin in 1974 with a grade summa cum laude and a PhD , also in biology, from the University of Virginia in 1977 . From 1977 to 1992 he was a research fellow at the Carnegie Institution of Washington in Washington, DC , interrupted from an activity from 1981 to 1983 at the Fred Hutchinson Cancer Research Center in Seattle , Washington . From 1988 to 1992 he also conducted research for the Howard Hughes Medical Institute . Between 1991 and 1996 he was director of research at Tularik Inc. , which he co-founded and which was sold to Amgen in 2004. McKnight has been Professor and Chair of Biochemistry at the University of Texas Southwestern Medical Center in Dallas since 1996 .

McKnight deals with the regulation of gene expression . In particular, he was able to clarify how the hypoxia-induced factor (HIF) is regulated via the oxygen supply.

Awards (selection)

Web links

Individual evidence

  1. ^ Eli Lilly and Company-Elanco Research Award Past Laureates ( Memento November 13, 2012 in the Internet Archive ) at the American Society for Microbiology (asm.org).
  2. ^ NAS Award in Molecular Biology from the National Academy of Sciences (nasonline.org); accessed on January 14, 2016
  3. Steven L. McKnight at the National Academy of Sciences (nasonline.org); Retrieved February 7, 2014
  4. Book of Members 1780 – present, Chapter M. (PDF; 1.1 MB) In: American Academy of Arts and Sciences (amacad.org). Retrieved May 16, 2019 .
  5. ^ The 13th Annual Wiley Prize in Biomedical Sciences Awarded for Advancements in Oxygen Sensing Systems. Wiley-Blackwell (wiley.com); Retrieved February 7, 2014