Thomas Benzing

Thomas Benzing (born May 12, 1965 in Schwenningen am Neckar ) is university professor and director of Clinic II for internal medicine ( nephrology , rheumatology , diabetology and general internal medicine) at Cologne University Hospital and director of the Center for Molecular Medicine Cologne (CMMC). Benzing is an internationally recognized nephrologist and deals with age research .

Life

Thomas Benzing studied medicine at the Albert-Ludwigs-Universität Freiburg , received his doctorate in 1993 ( investigations on the regulation of endothelial autacoid formation in cultivated endothelial cells ) and then worked as an assistant doctor at the Freiburg University Clinic until 1996, before joining the Institute as a research assistant at the Frankfurt University for cardiovascular physiology to Rudi Busse and then to Harvard University at the Beth Israel Hospital of Harvard Medical School . After returning from the USA, Benzing completed his habilitation in internal medicine at the University of Freiburg in 2002 and was then senior physician at the Clinic for Nephrology and General Medicine at the University Clinic Freiburg (headed by Gerd Walz ) and a Heisenberg fellow of the DFG. Benzing was u. a. at Harvard University in Boston, UT Southwestern in Dallas and Washington University in Seattle, but accepted an appointment as Professor of Medicine (W3) at the University of Freiburg in 2006, before becoming full professor and director of Clinic II for Internal medicine moved to Cologne. In 2011 he became director of the Center for Molecular Medicine in Cologne.

plant

Benzing is considered a pioneer in the field of molecular research into kidney diseases and has achieved an international reputation with his team through studies of the molecular causes of proteinuria , the function of the kidney filter and the molecular pathogenesis of cystic kidneys .

Honors, memberships, editorial work

He is co-editor of leading journals, member of the board of the CECAD (Cologne Cluster of Excellence on Cellular Stress Responses in Aging-Associated Diseases) on age-associated diseases at the University of Cologne and member of various scientific policy committees. Benzing was awarded high scientific prizes. In 2008 he received the Ernst Jung Prize for Medicine, in 2005 the Franz Volhard Prize of the German Society for Nephrology and in 2006 the Young Investigator Award of the American Society of Nephrology , of which he became a Fellow in 2005. In 2009 he became a member of the National Academy of Sciences Leopoldina and in 2015 he became a member of the American Society for Clinical Investigation . In 2020 Benzing was elected to the North Rhine-Westphalian Academy of Sciences and Arts .

Fonts (selection)

• with Gerd Walz u. a .: The polycystic kidney disease 1 gene product modulates Wnt signaling, Journal of Biological Chemistry, Volume 274, 1999, pp. 4947-4953
• with Tobias Huber , Michael Köttgen, Birgit Schilling, Gerd Walz: Interaction with podocin facilitates nephrin signaling, Journal of Biological Chemistry, Volume 276, 2001, pp. 41543-41546
• with Friedhelm Hildebrandt a. a .: Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination, Nature Genetics, Volume 34, 2003, pp. 413-420
• with Thomas Tuschl u. a .: A mammalian microRNA expression atlas based on small RNA library sequencing, Cell, Volume 129, 2007, pp. 1404-1414
• with Gerd Walz, Friedhelm Hildebrandt a. a .: Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis, Nature Genetics Volume 34, 2003, pp. 455-459
• Signaling at the slit diaphragm, Journal of the American Society of Nephrology, Vol. 15, 2004, 1382-1391
• with Tobias Huber: The slit diaphragm: a signaling platform to regulate podocyte function, Current opinion in nephrology and hypertension, Volume 14, 2005, 211-216
• with Gerd Walz u. a .: Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways, Nature Genetics, Volume 37, 2005, pp. 537-543
• with Manfred Fliegauf, Heymut Omram: When cilia go bad: cilia defects and ciliopathies, Nature reviews Molecular cell biology, Volume 8, 2007, pp. 880-893
• with RS Schwartz, F. Hildebrandt, N. Katsanis: Cilopathies, New England Journal of Medicine, Volume 364, 2011, pp. 1533-1543

Web links

• Laudation from Walter Hörl for the Volhard Prize
• CV at the Leopoldina, pdf
• Homepage University Hospital Cologne

Individual evidence

1. ↑ Member entry by Prof. Dr. Thomas Benzing (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on June 29, 2016.