6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

Structural formula
	Structural formula without stereochemistry
General
Surname	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
other names	Trolox; (±) -6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; ( RS ) -6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid;
Molecular formula	C 14 H 18 O 4
Brief description	white to beige powder
External identifiers / databases
EC number	258-422-8
ECHA InfoCard	100.053.094
PubChem	40634
ChemSpider	37117
Wikidata	Q245489
properties
Molar mass	250.29 g mol −1
Physical state	firmly
Melting point	187-194 ° C
solubility	soluble in water
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 315-319-335
	P: 261-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Trolox is a water soluble vitamin-E - derivative having the chemical name 6-hydroxy-2,5,7,8-tetramethylchroman-carboxylic acid 2- . The compound has a center of chirality on the C2 carbon atom.

use

Due to its pronounced antioxidant activity, Trolox is used as a reference substance when determining the antioxidant capacity of a sample ( TEAC test ).

Individual evidence

↑ ^a ^b ^c Trolox data sheet at Acros, accessed on February 3, 2018.
↑ ^a ^b Data sheet (±) -6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid from Sigma-Aldrich , accessed on February 3, 2018 ( PDF ).
↑ J Am Oil Chem Soc ., 1974, 51, p. 200.
↑ J Am Oil Chem Soc ., 1975, 52, p. 174.
↑ Food Technol ., Nov. 1975, p. 46.

[Acros-1] Trolox data sheet at Acros, accessed on February 3, 2018.

[Sigma-2] Data sheet (±) -6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid from Sigma-Aldrich , accessed on February 3, 2018 ( PDF ).

[JAOCS1974-3] J Am Oil Chem Soc ., 1974, 51, p. 200.

[JAOCS1975-4] J Am Oil Chem Soc ., 1975, 52, p. 174.

[FoodTechnol1975-5] Food Technol ., Nov. 1975, p. 46.