Oncovirus
As oncoviruses (singular: oncovirus), oncogenic viruses or tumor viruses referred to generally tumorigenic ( " carcinogenic ") virus . A certain subgroup of retroviruses used to be called this. However, this classification of retroviruses is out of date.
The name of the virus indicates its ability to induce tumors ( oncogenic ). The human oncoviruses in the broader sense include:
- the Epstein-Barr virus (EBV, corresponds to HHV-4)
- the hepatitis B virus (HBV)
- the hepatitis C virus (HCV)
- the human herpes virus 5 (HHV-5, synonym cytomegalovirus)
- the human herpesvirus 8 (HHV-8, also Kaposi sarcoma herpesvirus, KSHV)
- the human papilloma viruses (HPV, especially HPV-16 and HPV-18)
- the human T-lymphotropic virus 1 (HTLV-1)
- the human polyomavirus 1
- the human polyomavirus 2
- the Merkel cell polyomavirus (MCV or MCPyV)
- the SV40 (SV40), a zoonosis
- individual adenoviruses in non-natural host species , but not in humans.
Together, these oncoviruses are responsible for 10 to 15 percent of all human cancers worldwide , and according to estimates by the American Cancer Society even for around 17 percent of cancer cases.
literature
- Susanne Modrow, Dietrich Falke , Uwe Truyen: Molecular Virology. An introduction for biologists and medical professionals. 2nd Edition. Spectrum textbook, Heidelberg 2002, ISBN 3-8274-1086-X . (with references, English translation 2006) .
- David M. Knipe, Peter M. Howley et al. (Eds.): Fields' Virology , 2 volumes. 5th edition, Lippincott Williams & Wilkins, Philadelphia 2007, ISBN 978-0-7817-6060-7 ( standard work in virology) .
Web links
Individual evidence
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↑ D. Martin, JS Gutkind: Human tumor-associated viruses and new insights into the molecular mechanisms of cancer . In: Oncogene . 27, No. 2, 2008, pp. 31-42. PMID 19956178 .
Carl Zimmer: Cancer - a side effect of evolution? In: Spektrum der Wissenschaft 9, 2007, pp. 80–88.