Victor J. Hruby

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Victor J. Hruby (born December 24, 1938 in Valley City (North Dakota) ) is an American chemist (biochemistry). He is a professor at the University of Arizona .

Hruby studied at the University of North Dakota with a bachelor's degree in chemistry and mathematics in 1960 and master's degree in chemistry in 1962. He was in 1965 at Cornell University in Alfred Blomquist doctorate (Some Aspects of Benzocyclobutenes and Benzocyclobutadiene Chemistry). He then was an instructor at Cornell Medical College for Nobel Prize winner Vincent du Vigneaud . In 1968 he became an Assistant Professor, 1972 Associate Professor and 1977 Professor of Chemistry at the University of Arizona. Since 1989 he has been Regents Professor there and since 1978 also in the Department of Biochemistry and Molecular Biophysics, from 1981 at Arizona Research Laboratories, from 1988 also in the Department of Neuroscience and from 2005 also in the Department of Medical Pharmacology.

He deals with peptide hormones and neurotransmitters and their receptors and their role in diseases. In doing so, he synthesized a number of antagonists and mimetics that are important as drugs , which often only differ in the angular position of atoms in the molecule ( conformation ), but which greatly changes the biological effectiveness. To which he examined substances include opioids , melanocyte-stimulating hormone (MSH), glucagon , cholecystokinin (CCK), oxytocin and substance P .

He is a Fellow of the American Association for the Advancement of Science (1972) and the New York Academy of Sciences . In 1984/85 he was a Guggenheim Fellow (and visiting professor at Harvard) and in 1999/2000 he received a Humboldt Research Award , with which he was at the Technical University of Munich.

In 1988 he received the Arthur C. Cope Award , in 1988 the Merit Award from the National Institutes of Health , in 2002 the Ralph F. Hirschmann Award in Peptide Chemistry from the ACS, and in 1993 the Merrifield Award (then Pierce Award) from the American Peptide Society. In 2009 he was named Arizona Innovator of the Year. In 1989 he received an honorary doctorate from the Free University of Brussels. In 1974 he was President of the ACS (American Chemical Society). In 1992 he was visiting professor at Caltech with Peter Dervan .

Web links

Individual evidence

  1. biographical data, publications and Academic pedigree of Victor J. Hruby at academictree.org, accessed on February 12 2018th