William Greenough

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William B. Greenough III (born January 3, 1932 in Providence (Rhode Island) ) is an American medic. He is a specialist in the treatment of diarrheal diseases such as cholera in the developing world.

Greenough studied chemistry at Amherst College (bachelor's degree 1953) and medicine at Harvard Medical School (MD 1957). From 1962 to 1965 he was a surgeon for the US National Public Health Service (USNHS) at the Cholera Research Laboratory in Dhaka ( Bangladesh ) and then until 1967 at the National Institutes of Health (NIH). From 1967 to 1969 he was an assistant professor of medicine at Johns Hopkins University (and at city hospitals in Baltimore) and from 1969 to 1983 he was an associate professor of medicine and microbiology there. At the same time he was head of the infectious diseases department at Johns Hopkins Hospital from 1970 to 1976 (and at the same time at the NIH's NIAID, whose bacteriology and mycology department he headed from 1974 to 1976) and from 1977 to 1979 scientific director of the Cholera Research Center in Dhaka (whose advice he later also Board). From 1979 to 1985 he was director of the International Center for Diarrheal Disease Research in Dhaka. Since 1984 he has been a full professor of medicine at Johns Hopkins University. He is there in geriatrics at Johns Hopkins Bayview Medical Center and Professor of International Health at the Bloomberg School of Public Health at Johns Hopkins. In geriatrics he was involved in a long-term home care program (Hospital at Home), using his extensive experience from developing countries (for example in rehydration treatment and in general in the treatment of poorer population groups at low costs).

He dealt with cholera research and examined the mechanisms of action of the toxin released by the cholera bacteria . He was also involved in the development of effective methods of oral hydration (Oral Rehydration Therapy, ORT) for cholera and other diarrheal diseases, especially in Third World conditions (see WHO Drinking Solution ). The development of oral therapy was a novel idea at the time, although the problems with intravenous hydration were evident in the developing world. Greenough was part of a group of American medical professionals in Bangladesh in the 1960s when developing ORT. In the late 1970s he was also involved in the development of a rice-based ORT for developing countries (following a suggestion by Michael Field).

In 1983 he received the König Faisal Prize for Medicine for research on diarrheal diseases with John S. Fordtran and Michael Field . He worked with Field in the early 1970s on the effects of cholera toxin. In 1984 he received the Maurice Pate Prize from UNICEF . In 2001 he gave the Howard Florey Medal Lecture in Adelaide .

1983 to 1985 he was editor of the Journal of Diarrheal Disease Research.

From 1986 to 1994 he was President of the International Child Health Foundation, which he co-founded.

Web links

Individual evidence

  1. ^ National Institute of Allergy and Infectious Diseases
  2. This depends on the correct composition of the fluid, which is given to replace the fluid loss caused by the infection
  3. Joshua Ruxin Magic Bullet: The history of oral rehydration therapy , Medical History, Volume 38, 1994, p. 363, pdf
  4. Molla, Sarker, Hussain, Molla, Greenough The Lancet, 1982, Rahman, Bari, Molla, Greenough, The Lancet 1985
  5. Field, Greenough, Fromm, al-Awqati, J. Clinical Investigation, Volume 51, 1972