Zinc oil

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Zinc oil , Zinkoxidöl , ( latin Zinci oxidi oleum , oleum Zinci , oleum Zinci oxidati ) is a suspension of zinc oxide and olive oil , which in dermatology as a topical drug for wound treatment is employed.

Manufacturing

Zinc oil is only available in pharmacies and can be obtained without a prescription as a finished drug and as a prescription drug that is individually prepared by the pharmacist after prescription by a doctor or at the request of a patient .

According to the German Medicines Codex (DAC) and the New Formulation Form (NRF), zinc oil is a suspension of 50 parts of zinc oxide (300 sieve) in 50 parts of olive oil. The consistency can be increased by adding up to 3% highly dispersed silicon dioxide . Instead of olive oil - with its own strong odor - medium-chain triglycerides (neutral oil , Miglyol 812) that are less sensitive to oxidation can be used.

Storage and shelf life

A cool storage (8–15 ° C) is recommended to reduce auto-oxidation . According to the NRF, the shelf life is six months. Cold storage can impair the homogeneity of zinc oil due to constituents of the olive oil that crystallize out; it must then be warmed to room temperature before use. Zinc oil is an oily suspension and not a solution and should therefore be shaken before use, as zinc oxide sediments and deposits oil on the surface.

Areas of application

Due to the astringent , slightly antiseptic and desiccating (drying) effect of zinc oxide and the oily base, zinc oil has greasy and emollient properties. Indicated for diaper rash and dermatitis in intertriginous area , such softening shed crusts , for skin and wound treatment, such as leg ulcers, eczema , skin redness and irritation, as well as fissures and fissures .

See also

Individual evidence

  1. ^ ABDA - Federal Association of German Pharmacists' Associations (Ed.): German Medicines Codex (DAC) / New Formulation Form (NRF) . Govi, 2005, ISBN 3-7741-0044-6 .
  2. ↑ Christine Dorothée Haus: About the desiccating and occluding effects of shaking mixtures, zinc oil, polyethylene glycol gel DAB and a polyethylene glycol paste (pdf; 775 kB) 2002. Accessed on April 4, 2009.

literature

  • Alfred Fahr : Pharmaceutical technology for studies and work: with 109 tables . German Apotheker-Verlag, Stuttgart 2006, ISBN 3-7692-3511-8 .
  • Gernot Rassner: Dermatology: Textbook and Atlas; [Online access + interactive extras] . Elsevier, Urban and Fischer, Munich / Jena 2007, ISBN 978-3-437-42762-6 .

Web links

Wikibooks: Dermatology  - learning and teaching materials