UDP-xylose and UDP-N-acetylglucosamine transporter: Difference between revisions

SLC35B4
Identifiers
Aliases	SLC35B4, YEA, YEA4, solute carrier family 35 member B4
External IDs	OMIM: 610923; MGI: 1931249; HomoloGene: 5799; GeneCards: SLC35B4; OMA:SLC35B4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	134,316,930 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	34,154,046 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; middle temporal gyrus; ; Brodmann area 23; ; endothelial cell; ; placenta; ; retinal pigment epithelium; ; tibia; ; superior frontal gyrus; ; postcentral gyrus; ; pancreatic epithelial cell;
	Top expressed in
	saccule; ; otic placode; ; proximal tubule; ; yolk sac; ; kidney; ; secondary oocyte; ; superior frontal gyrus; ; thymus; ; cerebellar cortex; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; UDP-xylose transmembrane transporter activity; GDP-fucose transmembrane transporter activity; UDP-N-acetylglucosamine transmembrane transporter activity; 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; transmembrane transporter activity;
Cellular component	integral component of membrane; endoplasmic reticulum; membrane; integral component of Golgi membrane; integral component of endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane;
Biological process	UDP-xylose transmembrane transport; regulation of gluconeogenesis; carbohydrate transport; transmembrane transport; GDP-fucose transmembrane transport; UDP-N-acetylglucosamine transmembrane transport; 3'-phospho-5'-adenylyl sulfate transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	84912
	58246
	ENSG00000205060
	ENSMUSG00000018999
	Q969S0
	Q8CIA5
	NM_032826
	NM_021435
	NP_116215
	NP_067410
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 22:56, 16 April 2023

UDP-xylose and UDP-N-acetylglucosamine transporter is a protein that in humans is encoded by the SLC35B4 gene.^[5]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000205060 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000018999 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

Further reading[edit]

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ashikov A, Routier F, Fuhlrott J, et al. (2005). "The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine". J. Biol. Chem. 280 (29): 27230–5. doi:10.1074/jbc.M504783200. PMID 15911612.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. S2CID 69278.
Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B (2006). "Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family". Biochem. J. 400 (2): 281–9. doi:10.1042/BJ20060429. PMC 1652819. PMID 16965264.

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000205060 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000018999 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SLC35B4 solute carrier family 35, member B4".

[1]

[2]

[3]

[4]

[5]

@@ Line 1: / Line 1: @@
+{{Short description|Protein found in humans}}
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{Infobox_gene}}
-{{PBB_Controls
+'''UDP-xylose and UDP-N-acetylglucosamine transporter''' is a [[protein]] that in humans is encoded by the ''SLC35B4'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC35B4 solute carrier family 35, member B4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84912}}</ref>
-| update_page = yes
-| require_manual_inspection = no
-| update_protein_box = yes
-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Solute carrier family 35, member B4
- | HGNCid = 20584
- | Symbol = SLC35B4
- | AltSymbols =; FLJ14697; YEA; YEA4
- | OMIM =
- | ECnumber =
- | Homologene = 5799
- | MGIid = 1931249
- | Function = {{GNF_GO|id=GO:0005338 |text = nucleotide-sugar transmembrane transporter activity}} {{GNF_GO|id=GO:0005351 |text = sugar:hydrogen ion symporter activity}} {{GNF_GO|id=GO:0005462 |text = UDP-N-acetylglucosamine transmembrane transporter activity}} {{GNF_GO|id=GO:0005464 |text = UDP-xylose transmembrane transporter activity}}
- | Component = {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
- | Process = {{GNF_GO|id=GO:0006810 |text = transport}} {{GNF_GO|id=GO:0015780 |text = nucleotide-sugar transport}} {{GNF_GO|id=GO:0015788 |text = UDP-N-acetylglucosamine transport}} {{GNF_GO|id=GO:0015790 |text = UDP-xylose transport}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 84912
-    | Hs_Ensembl = ENSG00000205060
-    | Hs_RefseqProtein = NP_116215
-    | Hs_RefseqmRNA = NM_032826
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 7
-    | Hs_GenLoc_start = 133624632
-    | Hs_GenLoc_end = 133652343
-    | Hs_Uniprot = Q969S0
-    | Mm_EntrezGene = 58246
-    | Mm_Ensembl = ENSMUSG00000018999
-    | Mm_RefseqmRNA = NM_021435
-    | Mm_RefseqProtein = NP_067410
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 6
-    | Mm_GenLoc_start = 34079089
-    | Mm_GenLoc_end = 34107212
-    | Mm_Uniprot = Q8CB74
-  }}
-}}
-'''Solute carrier family 35, member B4''', also known as '''SLC35B4''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SLC35B4 solute carrier family 35, member B4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84912| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
 ==See also==
@@ Line 61: / Line 11: @@
 ==Further reading==
 {{refbegin | 2}}
+*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
-{{PBB_Further_reading
+*{{cite journal   |vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  }}
-| citations =
-*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
-*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
+*{{cite journal   |vauthors=Scherer SW, Cheung J, MacDonald JR, etal |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205  | pmc=2882961 |doi= 10.1126/science.1083423 |bibcode=2003Sci...300..767S }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
-*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Ashikov A, Routier F, Fuhlrott J, etal |title=The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. |journal=J. Biol. Chem. |volume=280 |issue= 29 |pages= 27230–5 |year= 2005 |pmid= 15911612 |doi= 10.1074/jbc.M504783200 |doi-access= free }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Otsuki T, Ota T, Nishikawa T, etal |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 |doi-access= free }}
-*{{cite journal  | author=Ashikov A, Routier F, Fuhlrott J, ''et al.'' |title=The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. |journal=J. Biol. Chem. |volume=280 |issue= 29 |pages= 27230-5 |year= 2005 |pmid= 15911612 |doi= 10.1074/jbc.M504783200 }}
+*{{cite journal   |vauthors=Oh JH, Yang JO, Hahn Y, etal |title=Transcriptome analysis of human gastric cancer. |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942–54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2 |s2cid=69278 }}
-*{{cite journal  | author=Otsuki T, Ota T, Nishikawa T, ''et al.'' |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117-26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117 }}
+*{{cite journal  | vauthors=Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B |title=Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family. |journal=Biochem. J. |volume=400 |issue= 2 |pages= 281–9 |year= 2006 |pmid= 16965264 |doi= 10.1042/BJ20060429  | pmc=1652819 }}
-*{{cite journal  | author=Oh JH, Yang JO, Hahn Y, ''et al.'' |title=Transcriptome analysis of human gastric cancer. |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942-54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2 }}
-*{{cite journal  | author=Kobayashi T, Sleeman JE, Coughtrie MW, Burchell B |title=Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family. |journal=Biochem. J. |volume=400 |issue= 2 |pages= 281-9 |year= 2006 |pmid= 16965264 |doi= 10.1042/BJ20060429 }}
-}}
 {{refend}}
-{{membrane-protein-stub}}
 {{Membrane transport proteins}}
 [[Category:Solute carrier family]]
+{{membrane-protein-stub}}

Latest revision as of 22:56, 16 April 2023

See also[edit]

References[edit]

Further reading[edit]