Zinc transporter 8: Difference between revisions
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'''Solute carrier family 30 (zinc transporter), member 8''', also known as '''SLC30A8''', is a human [[gene]]<ref name="entrez">{{cite web | title = Entrez Gene: SLC30A8 solute carrier family 30 (zinc transporter), member 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=169026| accessdate = }}</ref> that codes for a [[zinc]] [[Transport protein|transporter]] related to [[insulin]] secretion in humans. Certain [[allele]]s of this gene may increase the risk for developing [[Diabetes mellitus type 2|type 2 diabetes]], but loss-of-function |
'''Solute carrier family 30 (zinc transporter), member 8''', also known as '''SLC30A8''', is a human [[gene]]<ref name="entrez">{{cite web | title = Entrez Gene: SLC30A8 solute carrier family 30 (zinc transporter), member 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=169026| accessdate = }}</ref> that codes for a [[zinc]] [[Transport protein|transporter]] related to [[insulin]] secretion in humans. Certain [[allele]]s of this gene may increase the risk for developing [[Diabetes mellitus type 2|type 2 diabetes]], but a loss-of-function mutation appears to greatly reduce the risk of diabetes<ref>{{cite journal|last=Flannick|first=Jason|coauthors=et al.|title=Loss-of-function mutations in SLC30A8 protect against type 2 diabetes|journal=Nature Genetics|date=2014|doi=10.1038/ng.2915}}</ref> . |
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Revision as of 15:31, 3 March 2014
Solute carrier family 30 (zinc transporter), member 8, also known as SLC30A8, is a human gene[1] that codes for a zinc transporter related to insulin secretion in humans. Certain alleles of this gene may increase the risk for developing type 2 diabetes, but a loss-of-function mutation appears to greatly reduce the risk of diabetes[2] .
See also
References
- ^ "Entrez Gene: SLC30A8 solute carrier family 30 (zinc transporter), member 8".
- ^ Flannick, Jason (2014). "Loss-of-function mutations in SLC30A8 protect against type 2 diabetes". Nature Genetics. doi:10.1038/ng.2915.
{{cite journal}}
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Further reading
External links
- Type 2 diabetes genes mapped out, BBC News article