Mesulfen

Mesulfen
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	D10AB05 (WHO) P03AA03 (WHO) QP53AA01 (WHO);
Identifiers
	IUPAC name 2,7-Dimethylthianthrene;
CAS Number	135-58-0 ;
PubChem CID	67272;
ChemSpider	580870;
UNII	EG6V6W7WDD;
KEGG	D07212 ;
ECHA InfoCard	100.004.730
Chemical and physical data
Formula	C14H12S2
Molar mass	244.37 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Cc1ccc2c(c1)Sc3ccc(cc3S2)C;
	InChI InChI=1S/C14H12S2/c1-9-3-5-11-13(7-9)15-12-6-4-10(2)8-14(12)16-11/h3-8H,1-2H3; Key:AHXDSVSZEZHDLV-UHFFFAOYSA-N;
	(verify)

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Mesulfen (2,7-dimethylthianthrene) is an anti-acne preparation,^[1] as well as a scabicide.^[2] It is a dimethyl derivative of thianthrene.^{[citation needed]}

References

^ Leoni A, Dudine G (1983). "[Therapy of seborrhea, seborrheic eczema and acne with a soap with a mesulfen base]". Giornale Italiano di Dermatologia e Venereologia. 118 (2): XXI–XXIV. PMID 6226594.
^ Meneghini CL, Vena GA, Angelini G (July 1982). "Contact dermatitis to scabicides". Contact Dermatitis. 8 (4): 285–6. doi:10.1111/j.1600-0536.1982.tb04231.x. PMID 7105702. S2CID 40211902.

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[1] Leoni A, Dudine G (1983). "[Therapy of seborrhea, seborrheic eczema and acne with a soap with a mesulfen base]". Giornale Italiano di Dermatologia e Venereologia. 118 (2): XXI–XXIV. PMID 6226594.

[2] Meneghini CL, Vena GA, Angelini G (July 1982). "Contact dermatitis to scabicides". Contact Dermatitis. 8 (4): 285–6. doi:10.1111/j.1600-0536.1982.tb04231.x. PMID 7105702. S2CID 40211902.

[1]

[2]

v t e Acne-treating agents (D10)
Antibacterial	Azelaic acid Benzoyl peroxide^# 8-Hydroxyquinoline Blue light therapy Tea tree oil
Keratolytic	Glycolic acid Salicylic acid^# Sulfur Benzoyl peroxide^#
Anti-inflammatory	Niacinamide Ibuprofen^# Aspirin^# Red light therapy
Antibiotics	Clindamycin Dapsone Erythromycin Sulfacetamide Tetracyclines (Lymecycline Minocycline Doxycycline)
Hormonal	Antiandrogens Bicalutamide Cyproterone acetate Drospirenone Flutamide Spironolactone) Estrogens Estradiol Ethinylestradiol
Retinoids	Adapalene Isotretinoin Motretinide Tazarotene Tretinoin Trifarotene
Other	Epristeride Mesulfen Pelretin Stridex Tioxolone
Combinations	Adapalene/benzoyl peroxide Clindamycin/adapalene/benzoyl peroxide Clindamycin/benzoyl peroxide Clindamycin/tretinoin Erythromycin/benzoyl peroxide Erythromycin/isotretinoin Sulfacetamide/sulfur Tretinoin/benzoyl peroxide
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III