1-docosanol
Structural formula | ||||||||||||||||||||||
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General | ||||||||||||||||||||||
Surname | 1-docosanol | |||||||||||||||||||||
other names |
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Molecular formula | C 22 H 46 O | |||||||||||||||||||||
Brief description |
white solid |
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Drug information | ||||||||||||||||||||||
ATC code | ||||||||||||||||||||||
properties | ||||||||||||||||||||||
Molar mass | 326.60 g mol −1 | |||||||||||||||||||||
Physical state |
firmly |
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density |
0.8063 g cm −3 (75 ° C) |
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Melting point |
65-72 ° C |
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boiling point |
180 ° C (0.29 hPa) |
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solubility |
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safety instructions | ||||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
1-Docosanol is a chemical compound from the group of fatty alcohols .
Occurrence
1-Docosanol was isolated from Clematis brevicaudata .
Extraction and presentation
1-Docosanol can be obtained by reducing behenic acid with lithium aluminum hydride .
properties
1-Docosanol is a white solid that is insoluble in water.
use
1-Docosanol can be used to synthesize a number of amphiphilic dendrimers . It is also used as an active ingredient from the group of antivirals for the external treatment of cold sores (herpes).
Individual evidence
- ↑ Entry on BEHENYL ALCOHOL in the CosIng database of the EU Commission, accessed on May 26, 2020.
- ↑ a b c d e f g h i Data sheet 1-Docosanol, 98% from Sigma-Aldrich , accessed on May 6, 2015 ( PDF ).
- ↑ a b c d e Entry on 1-docosanol in the Hazardous Substances Data Bank , accessed on May 6, 2015.
- ↑ DT Leung, SL Sacks: Docosanol: a topical antiviral for herpes labialis. In: Expert Opin Pharmacother . 5, 2004, pp. 2567-2571, PMID 15571473 .