3,5-dinitroanisole
| Structural formula | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|||||||||||||
| General | |||||||||||||
| Surname | 3,5-dinitroanisole | ||||||||||||
| other names |
|
||||||||||||
| Molecular formula | C 7 H 6 N 2 O 5 | ||||||||||||
| External identifiers / databases | |||||||||||||
|
|||||||||||||
| properties | |||||||||||||
| Molar mass | 198.13 g mol −1 | ||||||||||||
| Physical state |
firmly |
||||||||||||
| Melting point |
105 ° C |
||||||||||||
| safety instructions | |||||||||||||
|
|||||||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||
3,5-Dinitroanisole is a solid with a melting point of 105 ° C. It is derived from both anisole (methoxybenzene) and nitrobenzene or dinitrobenzenes . The structure consists of a benzene ring with a methoxy group (-OCH 3 ) and two nitro groups (-NO 2 ) as substituents .
presentation
3,5-Dinitroanisole is prepared by reacting 1,3,5-Trinitrobenzene with sodium methoxide in abs. Methanol .
Reactions
The nitration of 3,5-dinitroanisole with nitric acid and sulfuric acid leads to 2,3,5-trinitroanisole .
use
3,5-dinitroanisole is an intermediate in the preparation of an inhibitor of catechol- O used -methyl-transferase (COMT) 3,5-Dinitrobrenzcatechins .
Individual evidence
- ↑ a b Frederic Reverdin: 3,5-Dinitroanisole In: Organic Syntheses . 7, 1927, p. 28, doi : 10.15227 / orgsyn.007.0028 ; Coll. Vol. 1, 1941, p. 219 ( PDF ).
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ a b M. H. Vermeulen: "Sur la structure des dinitranisols", in: Rec. Trav. Chim. , 1906 , 25 , pp. 12-31; Full text .
- ↑ a b M. H. Vermeulen: "Sur quelques trinitranisols", in: Rec. Trav. Chim. , 1912 , 31 , pp. 101-104; Full text .
- ↑ Data sheet 3,5-Dinitroanisol from Sigma-Aldrich , accessed on July 16, 2010 ( PDF ).