3-hydroxypropionic acid

Structural formula
General
Surname	3-hydroxypropionic acid
other names	3-HP
Molecular formula	C 3 H 6 O 3
External identifiers / databases
EC number	207-974-8
ECHA InfoCard	100.007.250
PubChem	68152
ChemSpider	61460
DrugBank	DB03688
Wikidata	Q2823220
properties
Molar mass	90.08 g mol −1
Physical state	firmly
density	1.066 g cm −3 (25 ° C)
Melting point	213 ° C
pK s value	4.50 (25 ° C)
Refractive index	1.364 (20 ° C)
safety instructions
H and P phrases	H: 302-315-318-335
	P: 261-280-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

3-Hydroxypropionic acid is a chemical compound from the group of β- hydroxycarboxylic acids .

Extraction and presentation

3-Hydroxypropionic acid does not occur naturally, but can be obtained biotechnologically with the help of E. coli from pyruvate via L - alanine , β-alanine and malonic acid semialdehyde.

use

3-hydroxypropionic acid can be used in the production of 1,3-propanediol , biopolymers and acrylics .

Individual evidence

↑ ^a ^b ^c ^d data sheet 3-Hydroxypropionic acid, 30% solution in water from Sigma-Aldrich , accessed on December 26, 2016 ( PDF ).
↑ ^a ^b ^c Rolf D. Schmid: Pocket Atlas of Biotechnology and Genetic Engineering . John Wiley & Sons, 2016, ISBN 978-3-527-33678-4 ( limited preview in Google Book Search).
↑ Chan Woo Song, Je Woong Kim, In Jin Cho, Sang Yup Lee: Metabolic Engineering of Escherichia coli for the Production of 3-Hydroxypropionic Acid and Malonic Acid through β-Alanine Route. In: ACS Synthetic Biology. 2016, Volume 5, Number 11, pp. 1256-1263. doi : 10.1021 / acssynbio.6b00007 .
↑ Cristina Della Pina, Ermelinda Falletta, Michele Rossi: A green approach to chemical building blocks. The case of 3-hydroxypropanoic acid. In: Green Chemistry. 13, 2011, p. 1624, doi : 10.1039 / C1GC15052A .

[Sigma-1] ta sheet 3-Hydroxypropionic acid, 30% solution in water from Sigma-Aldrich , accessed on December 26, 2016 ( PDF ).

[Rolf_D._Schmid-2] Rolf D. Schmid: Pocket Atlas of Biotechnology and Genetic Engineering . John Wiley & Sons, 2016, ISBN 978-3-527-33678-4 ( limited preview in Google Book Search).

[DOI10.1021/acssynbio.6b00007-3] Chan Woo Song, Je Woong Kim, In Jin Cho, Sang Yup Lee: Metabolic Engineering of Escherichia coli for the Production of 3-Hydroxypropionic Acid and Malonic Acid through β-Alanine Route. In: ACS Synthetic Biology. 2016, Volume 5, Number 11, pp. 1256-1263. doi : 10.1021 / acssynbio.6b00007 .

[DOI10.1039/C1GC15052A-4] Cristina Della Pina, Ermelinda Falletta, Michele Rossi: A green approach to chemical building blocks. The case of 3-hydroxypropanoic acid. In: Green Chemistry. 13, 2011, p. 1624, doi : 10.1039 / C1GC15052A .