4- (dimethylamino) azobenzene-4'-isothiocyanate

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Structural formula
Structural formula of DABITC
General
Surname 4- (dimethylamino) azobenzene-4'-isothiocyanate
other names
  • 4 - [(4-Isothiocyanatophenyl) diazenyl] - N , N -dimethylaniline ( IUPAC )
  • 4- (dimethylamino) azobenzene-4'-isothiocyanate
Molecular formula C 15 H 14 N 4 S
External identifiers / databases
CAS number 7612-98-8
EC number 231-521-3
ECHA InfoCard 100.028.656
PubChem 82084
ChemSpider 21172708
Wikidata Q27902939
properties
Molar mass 282.36 g mol −1
Physical state

firmly

Melting point

167-171 ° C

safety instructions
GHS labeling of hazardous substances
08 - Dangerous to health

danger

H and P phrases H: 317-334
P: 261-280-342 + 311
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4- (Dimethylamino) azobenzene-4'-isothiocyanate (DABITC) is a chemical compound from the group of isothiocyanates . It is used in Edman degradation and the marking of molecules for colored derivatisation of amino groups in proteins and amino acids .

Individual evidence

  1. ↑ a b c Data sheet 4- (4-Isothiocyanatophenylazo) -N, N-dimethylaniline, 97% from Sigma-Aldrich , accessed on October 20, 2016 ( PDF ).
  2. ↑ JY Chang, EH Creaser: A novel manual method for protein-sequence analysis. In: Biochem J. 157, No. 1, 1976, pp. 77-85, PMID 822842 , PMC 1163818 (free full text).