5-chloruracil
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| General | ||||||||||||||||
| Surname | 5-chloruracil | |||||||||||||||
| other names |
5-chloro-1 H -pyrimidine-2,4-dione ( IUPAC ) |
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| Molecular formula | C 4 H 3 ClN 2 O 2 | |||||||||||||||
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| properties | ||||||||||||||||
| Molar mass | 146.53 g mol −1 | |||||||||||||||
| Physical state |
firmly |
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| Melting point |
> 300 ° C (decomposition) |
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||||||||
5-Chloruracil is a heterocyclic organic compound with a pyrimidine backbone and two carbonyl groups in positions 2 and 4 and a chlorine in position 5. It is a derivative of the nucleobase uracil . It acts as an antimetabolite or base analog , it acts as a substitute for thymine in DNA and can produce DNA mutations in the same way as 5-bromouracil .
Individual evidence
- ↑ a b c Data sheet 5-chloruracil (PDF) from Merck , accessed on March 18, 2011.