Albert JR Heck

Albert Heck

Albert JR Heck (born November 26, 1964 in Goes ) is a Dutch biochemist .

Heck studied chemistry at the Free University of Amsterdam and received his doctorate from the University of Amsterdam in 1993. He was a post-doctoral student at Stanford University with Richard Zare and at Sandia National Laboratories . He was a lecturer at the University of Warwick and in 1998 became a professor at the University of Utrecht .

He heads the group for biomolecular mass spectrometry and proteomics in Utrecht . From 2003 he was Scientific Director of the Dutch Proteomics Center and from 2006 to 2012 he was Scientific Director of the Bijvoet Center for Biomolecular Research at the University of Utrecht.

He and his group were among the pioneers of native mass spectrometry , in which biomolecules are not only analyzed according to their mass, but also the structure of non- covalent protein- protein complexes and protein- ligand complexes, for example antibody - antigen complexes . In proteomics he is known for the analysis of post-translational modifications (especially phosphorylations ) of proteins with mass spectrometry and the development of novel peptide fragmentation strategies to clarify specific post-translational modifications.

In 2017 he received the Spinoza Prize . He is a member of the Dutch Academy of Sciences and the European Molecular Biology Organization .

Fonts (selection)

with RH van den Heuvel: Native protein mass spectrometry: from intact oligomers to functional machineries, Curr. Opin. Chem. Biol., Vol. 8, 2004, pp. 519-526
Native mass spectrometry: a bridge between interactomics and structural biology, Nature Methods, Volume 5, 2008, pp. 927-933.

Web links

Heck Lab

Individual evidence

↑ The term Native Mass Spectrometry was introduced in the article: Leney, Heck, Native Mass Spectrometry: What is in the Name?, J. Am. Soc. Mass Spectrometry, Volume 28, 2017, pp. 5–13, PMC 5174146 (free full text)

personal data
SURNAME	Heck, Albert JR
BRIEF DESCRIPTION	Dutch biochemist
DATE OF BIRTH	November 26, 1964
PLACE OF BIRTH	Goes

[1] The term Native Mass Spectrometry was introduced in the article: Leney, Heck, Native Mass Spectrometry: What is in the Name?, J. Am. Soc. Mass Spectrometry, Volume 28, 2017, pp. 5–13, PMC 5174146 (free full text)