Alfred Nordheim

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Alfred Nordheim (born December 1, 1951 in Philippsthal (Werra) ) is a German molecular and cell biologist and professor at the Eberhard Karls University of Tübingen .

Life

Alfred Nordheim studied biology at the Free University of Berlin and received his doctorate in 1979, Dr. rer. nat. (Dissertation at the Max Planck Institute for Molecular Genetics , Berlin-Dahlem, supervised by Prof. Kenneth Timmis). He worked for four years as a post-doc at the Massachusetts Institute of Technology (Alex Rich Group, MIT, Boston, USA). He then spent five years (1984–1989) as a group leader at the ZMBH at Heidelberg University and a further seven years (1989–1996) as head of the Institute for Molecular Biology at the Hannover Medical School (MHH). Since 1996 he has held the chair for molecular biology at the Interfaculty Institute for Cell Biology (IFIZ) at the Eberhard Karls University in Tübingen. Nordheim was President of the German Society for Genetics (GfG) (2005–2009) and the International Genetics Federation (IGF; Melbourne, Australia) (2008–2013). He is Secretary General of the International Genetics Federation (IGF; since 2013). He is co-founder of the biotechnology company ProteoSys AG, Mainz. Nordheim has been Scientific Director at the Leibniz Institute for Aging Research - Fritz Lipmann Institute in Jena since March 2018 .

Research priorities

Nordheim is studying the molecular processes that enable the correct reading of genetic information in mammalian cells . The animal model system of the mouse ( M. musculus ) is used for this. The knowledge gained contributes to the understanding of human diseases, e.g. B. the development of cancer.

Honourings and prices

Alfred Nordheim has been an elected member of the European Molecular Biology Organization (EMBO) since 1991 and was awarded the Max Planck Research Prize together with Robert Allan Weinberg (MIT) in 1992 .

Fonts

  • Alberti, S. et al. 2005. Neuronal migration in the murine rostral migration stream requires serum response factor. Proc. Natl. Acad. Sci. USA 102: 6148-6153.
  • Olson, EN, and Nordheim, A. 2010. Linking actin dynamics and gene transcription to drive cellular motile functions. Nat. Rev. Mol. Cell Biol. 11: 353-365
  • Weinl, C. et al. 2013. Endothelial SRF / MRTF ablation cause vascular disease phenotypes in murine retinae, Journal of Clinical Investigation 123: 2193-2206
  • Crossing boundaries: humans in the field of tension between biology, culture and technology. Edited by Alfred Nordheim and Klaus Antoni . Transcript Verlag, Bielefeld 2013, ISBN 978-3-8376-2260-7
  • Ohrnberger, S. et al. 2015. Dysregulated Serum Response Factor Triggers Formation of Hepatocellular Carcinoma. Hepatology 61: 979-989.
  • Molecular Genetics, 10th edition, eds. Alfred Nordheim and Rolf Knippers (with the collaboration of Peter Dröge, Gunter Meister, Elmar Schiebel, Martin Vingron , Jörn Walter), Thieme Verlag, Stuttgart 2015, ISBN 9783134770100 .

Web links

personal data
SURNAME Nordheim, Alfred
BRIEF DESCRIPTION German molecular biologist and geneticist
DATE OF BIRTH December 1, 1951
PLACE OF BIRTH Philippsthal (Werra)