Leibniz Institute for Aging Research

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Leibniz Institute for Aging Research
Fritz Lipmann Institute
Category: research Institute
Carrier: legally independent
Legal form of the carrier: Registered association
Membership: Leibniz Association
Facility location: Jena
Type of research: Basic research
Subjects: Natural sciences , life sciences
Areas of expertise: Gerontology , biomedicine
Basic funding: Federal government (50%), states (50%)
Management: Alfred Nordheim (scientific)
Daniele Barthel (adm.)
Employee: approx. 330
Homepage: www.leibniz-fli.de
Leibniz Institute for Aging Research (FLI) in Jena
Leibniz Institute for Aging Research (FLI), new building, in Jena

The Leibniz Institute for Aging Research - Fritz Lipmann Institute (FLI) is a non-university research facility based on the Beutenberg campus in Jena and is assigned to application-oriented basic research in the life sciences . The institute is a member of the Gottfried Wilhelm Leibniz Scientific Community (WGL). The FLI is managed in a private legal form as a registered association .

The FLI is the first national research institute devoted to biomedical research in the field of aging research / gerontology on a broad scale . The institute is located on the Beutenberg campus in Jena .

history

After reunification , the former Central Institute for Microbiology and Experimental Therapy (ZIMET) of the Academy of Sciences of the GDR was essentially divided into two institutes in 1991: the Hans Knöll Institute (HKI) and the Institute for Molecular Biotechnology (IMB). The IMB was focused on research in the field of evolutionary biotechnology and genome sciences and since January 1992 has been one of the research institutions jointly supported by the federal government and the federal states in what was then the "Blue List", today's Leibniz Association.

After an evaluation , the Science Council suggested in 1999 that a new research concept be drawn up for the IMB. As a result, in 2003 Peter Herrlich was appointed the new director of the IMB, who had proposed the new scientific concept "Mechanisms of aging and age-related diseases". In accordance with its new scientific orientation, the institute was renamed "Leibniz Institute for Aging Research - Fritz Lipmann Institute" (FLI) in 2005.

The institute is named after the German-American biochemist Fritz Lipmann (1899–1986), who received the Nobel Prize in Medicine in 1953 for his discovery of coenzyme A and its importance for intermediate metabolism.

Research and Development

The overarching goal of the FLI is to analyze the mechanisms of critical, particularly pathological , processes from which conclusions about health and healthy aging can be drawn.

Within this broad field of research, specific topics are selected, which are organizationally divided into two program priorities, but which are closely linked due to their scientific content and methodology. One example of this is the “Aging of cells and organisms” focus, in which the stability of genomes and telomeres is being investigated by several research groups at various levels. In addition, the epigenetic control of genes is examined , primarily using genomic approaches, and new genes that are involved in the aging process are identified. The focus “Specific age-related diseases” deals with selected examples of age-related diseases . Mechanisms that lead to protein folding diseases are currently being investigated , e.g. B. amyloidoses , Alzheimer's and Huntington 's disease and other neurodegenerative diseases. Cancer and various organ failures are being researched on other age-related diseases .

Cooperations

A multidisciplinary approach is the foundation of research at the FLI and is reflected in a large number of national and international collaborations with other research institutions.

The FLI works closely with the Friedrich Schiller University Jena (FSU) and the “Association of Biomedical Research” in Jena. Scientists from the FLI are involved in teaching at the FSU.

The university is also involved in the newly established “Leibniz Graduate School for Aging and Aging Diseases” at the FLI.

Infrastructure

Until 2017 the institute was headed by the scientific director Karl Lenhard Rudolph , the administrative director is Daniele Barthel. The Board of Trustees of the Leibniz Institute for Aging Research - Fritz Lipmann Institute eV decided unanimously in July 2017 to fill the position of Scientific Director due to the discovery of scientific misconduct by the previous Scientific Director.

Around 330 people work at the institute, including around 170 scientists from 30 nations.

The institute's budget in 2011 was 24.4 million euros (plus 8 million euros for construction work), of which around 20 million euros were funded by the federal government ( BMBF ) and half by the federal states. Around 3 million euros were acquired as third-party funding.

Web links

Commons : Leibniz Institute for Aging Research  - Collection of images, videos and audio files

Individual evidence

  1. Ralf Neumann: No more mistakes! In: Laborjournal. June 17, 2017. Retrieved June 20, 2017 .
  2. Julia Merlot: Leibniz director loses his post. In: Spiegel Online. July 27, 2017. Retrieved July 29, 2017 .

Coordinates: 50 ° 54 ′ 29.9 ″  N , 11 ° 34 ′ 18.5 ″  E