Alfred Puhler

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Alfred Pühler (born September 28, 1940 in Nuremberg ) is a German microbiologist , geneticist and biotechnologist . He is one of the pioneers of modern genetic engineering , biotechnology and genome research in biotechnologically relevant microorganisms and was significantly involved in deciphering the genome sequence of several microorganisms.

biography

Alfred Pühler studied physics at the University of Erlangen-Nürnberg , in 1971 he did his doctorate in microbiology on the topic of the competence of donor and recipient in Rhizobium lupini conjugation and in 1977 he completed his habilitation in genetics with the habilitation thesis The behavior of the resistance factor RP 4 from Pseudomonas aeruginosa in the soil bacterium Rhizobium lupini and in the enterobacterium Escherichia coli . In 1979 Pühler was appointed to the chair of genetics at Bielefeld University, where he worked until 2008. From 1985 to 1986 he was Dean of the Faculty of Biology, from 1992 to 1994 Vice Rector for Research and Young Scientists at the University.

From 1988 to 1996 Pühler was elected expert reviewer for the field of "General Biology, Genetics and Cell Biology" of the German Research Foundation (DFG). In 1995 he was a member of the Central Commission for Biosafety (ZKBS) and from 1999 to 2005 he was elected member of the Scientific Commission of the Science Council . In 2008 Pühler was appointed Foreign Secretary of the Union of German Academies of Sciences . In 2004 he became the spokesman for the Center for Biotechnology at Bielefeld University (CeBiTec), which he had largely built up, and after his retirement he moved to CeBiTec as Senior Research Professor. He is also the coordinator of the German network for bioinformatics infrastructure - de.NBI , which is the German hub in the Europe-wide bioinformatics network ELIXIR .

research

Alfred Pühler is one of the pioneers of modern genetic engineering , biotechnology and genome research in biotechnologically relevant microorganisms, including the symbiotic nitrogen-fixing rhizobia , xanthan-forming xanthomonads and amino acid-producing corynebacteria . He was involved in deciphering the genome of various bacteria, including Sinorhizobium meliloti , Corynebacterium glutamicum and Xanthomonas campestris

Awards

Since 1993 Pühler has been a member of the North Rhine-Westphalian Academy of Sciences and Arts , since 1999 of the German Academy of Natural Scientists Leopoldina , and since 2004 of the German Academy of Science and Engineering (acatech) .

Fonts

In addition to a large number of specialist publications, Alfred Pühler also published numerous books as an author, co-author and editor:

  • Alfred Pühler (Hrsg.): Römpp compact Lexicon Biochemistry and Molecular Biology. Thieme Verlag, Stuttgart 2000.
  • Wolfgang van den Daele , Alfred Pühler, Herbert Sukopp : Transgenic herbicide resistant crops: a participatory technology assessment; summary report. Publication of the department for standardization and the environment of the research focus technology, work, environment of the Berlin Science Center for Social Research, 1997.
  • Inge Broer, Alfred Pühler: Stability of HR genes in transgenic plants and their spontaneous horizontal gene transfer to other organisms. Publication of the department for standardization and the environment of the research focus technology, work, environment of the Berlin Science Center for Social Research, 1994.
  • Alfred Pühler (Ed.): Genetic engineering of animals. Wiley-VCH, Weinheim 1993.
  • Alfred Pühler (Ed.): Genetic engineering of microorganisms. Wiley-VCH, Weinheim 1993.
  • Alfred Pühler: Bacteria-plant interaction: Analysis of the signal exchange between the symbiotic partners during the formation of alfalfa nodules. Westdeutscher Verlag, Opladen 1993
  • Alfred Pühler (Ed.): Biotechnology. Vol. 2. Genetic fundamentals and genetic engineering. Wiley-VCH, Weinheim 1993.
  • Alfred Pühler (Ed.): Safety in Biotechnology / Biological Basics. BioTechForum Vol. 2: Practice of Biotechnology, Hüthig-Verlag, Heidelberg 1991
  • Alfred Pühler, KN Timmis (Ed.): Advanced molecular genetics. Springer-Verlag, Berlin 1984.
  • Alfred Pühler (Ed.): Molecular genetics of the bacteria plant interaction. Springer-Verlag, Berlin 1983.
  • Alfred Pühler: The behavior of the resistance factor RP 4 from Pseudomonas aeruginosa in the soil bacterium Rhizobium lupini and in the enterobacterium Escherichia coli. University of Erlangen-Nuremberg, Department of Biology a. Chemistry, habilitation thesis 1976.
  • Alfred Pühler: The competence of the donor and recipient in Rhizobium-lupini conjugation. University of Erlangen-Nuremberg, Department of Biology a. Chemistry, dissertation 1971.

Alfred Pühler is also editor-in-chief of the Journal of Biotechnology .

Web links

Individual evidence

  1. ↑ a b c d curriculum vitae at the North Rhine-Westphalian Academy of Sciences
  2. ↑ Torsten Schlatzke: Alfred Pühler appointed Foreign Secretary of the Union of German Academies of Sciences . Press release Bielefeld University at the Science Information Service (idw), July 22, 2008.
  3. ↑ Torsten Schlatzke: Ceremonial colloquium for genome researcher Alfred Pühler . Press release Bielefeld University at the Science Information Service (idw), October 23, 2008.
  4. ↑ de.NBI coordinator. Retrieved February 12, 2019 .
  5. ↑ ELIXIR Board meeting: 2016 Spring session | ELIXIR. Retrieved February 12, 2019 .
  6. ^ F. Galibert, A. Pühler, J. Batut: The Composite Genome of the Legume Symbiont Sinorhizobium meliloti, Science 293, 2001; Pp. 668-672.
  7. ↑ J. Kalinowski, A. Pühler, A. Tauch: The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins, in: Journal of Biotechnology 104, 2003; Pp. 5-25.
  8. ↑ F.-J. Vorhölter, A. Pühler: The genome of Xanthomonas campestris pv. Campestris B100 and its use for the reconstruction of metabolic pathways involved in xanthan biosynthesis, in: Journal of Biotechnology 134, 2008, pp. 33-45.
  9. ↑ Member entry by Prof. Dr. Alfred Pühler (with picture and CV) at the Deutsche Akademie der Naturforscher Leopoldina , accessed on July 16, 2016.
  10. ^ Federal Cross of Merit for Genome Researcher Alfred Pühler. Genomxpress 3.09, 2009; P. 40.
  11. ↑ Comprehensive list on the homepage of Alfred Pühler at the Center for Biotechnology at Bielefeld University (CeBiTec).
  12. ↑ List of literature based on the list of publications of the German National Library
personal data
SURNAME Puhler, Alfred
BRIEF DESCRIPTION German microbiologist, geneticist, biotechnologist and university professor
DATE OF BIRTH September 28, 1940
PLACE OF BIRTH Nuremberg