Allobarbital

Structural formula
General
Non-proprietary name	Allobarbital
other names	5,5-Di-2-propenyl (1 H , 3 H , 5 H ) -pyrimidine-2,4,6-trione; 5,5-diallyl barbituric acid;
Molecular formula	C 10 H 12 N 2 O 3
External identifiers / databases
EC number	200-140-4
ECHA InfoCard	100,000,129
PubChem	5842
Wikidata	Q418905
Drug information
ATC code	N05 CA21
Drug class	sedative
properties
Molar mass	208.21 g mol −1
Physical state	firmly
Melting point	171-173 ° C
solubility	Easily soluble in ethanol and hot water
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances danger
H and P phrases	H: 301
	P: 301 + 310
Toxicological data	127.3 mg kg −1 ( LD 50 , rat , ip )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Allobarbital is a drug from the group of barbiturates . It has a strong sedative effect. Allobarbital was patented by CIBA in 1912 and used as a sleep aid (Dial ^® ) and as a component of pain relievers (Cibalen ^® , Cibalgin ^® ). It is one of the barbiturates with a medium-long duration of action (2–8 h). Because of the narrow therapeutic range , the side effect profile and the addictive potential, it is now subject to the narcotics prescription regulation. It has not been approved as a sleeping pill in Germany or Switzerland since 1992.

Legal status

Allobarbital is a marketable and prescription narcotic drug in the Federal Republic of Germany due to its listing in Appendix 3 BtMG. Handling without permission or prescription is generally punishable. Further information can be found in the main article Narcotics Law in Germany .

Internationally, allobarbital falls under the Convention on Psychotropic Substances .

Individual evidence

↑ ^a ^b ^c Entry on allobarbital. In: Römpp Online . Georg Thieme Verlag, accessed on September 30, 2014.
↑ Claudia Synowietz (Ed.): Paperback for chemists and physicists . founded by Jean d'Ans, Ellen Lax. 4th edition. Volume II: Organic Compounds . Springer, Berlin 1983, ISBN 3-540-12263-X .
↑ ^a ^b Data sheet 5,5-Diallylbarbituric acid from Sigma-Aldrich , accessed on November 5, 2016 ( PDF ).
↑ Red List 1969, Federal Association of the Pharmaceutical Industry eV, Editio Cantor, Aulendorf, 1969
↑ Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976 ISBN 3-13-520601-7

[RÖMPP_Online-1] Entry on allobarbital. In: Römpp Online . Georg Thieme Verlag, accessed on September 30, 2014.

[2] Claudia Synowietz (Ed.): Paperback for chemists and physicists . founded by Jean d'Ans, Ellen Lax. 4th edition. Volume II: Organic Compounds . Springer, Berlin 1983, ISBN 3-540-12263-X .

[Sigma-3] Data sheet 5,5-Diallylbarbituric acid from Sigma-Aldrich , accessed on November 5, 2016 ( PDF ).

[4] Red List 1969, Federal Association of the Pharmaceutical Industry eV, Editio Cantor, Aulendorf, 1969

[5] Eberhard Schröder, Clemens Rufer, Ralph Schmiechen, Arzneimittelchemie I, Georg Thieme Verlag 1976 ISBN 3-13-520601-7