A. Dale Kaiser

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Armin Dale Kaiser (born November 10, 1927 in Piqua , Ohio - † June 5, 2020 in Stanford , California ) was an American biochemist, molecular geneticist, microbiologist and developmental biologist.

Kaiser graduated from Purdue University ( bachelor's degree in 1950) and received his PhD in biology and chemistry from Caltech in 1955 . At Caltech he was in Max Delbrück's bacteriophage group and worked particularly with Jean Weigle. In 1956 he was a post-doctoral student at the Pasteur Institute in Paris (where he worked with Francois Jacob , also in the bacteriophage group) and then first instructor and then assistant professor of microbiology at Washington University in St. Louis . From 1959 he was at Stanford University , where he received a full professorship in biochemistry at the Medical School in 1966 . From 1989 he held a professorship for Development Biology there .

Kaiser initially dealt intensively with the molecular genetics of the lambda phage . In particular, he investigated the control mechanisms of phage lysogeny . In doing so, he found one of the earliest examples of the self-regulation of a gene (cI, the repressor gene of the lambda phage) and what were later known as chaperone proteins. Some of the methods developed in his laboratory were widely used in genetic engineering.

In the 1970s he turned to the development of multicellular organisms, which he did not research on eukaryotes , but on myxobacteria . In the 2000s, he and his laboratory in Stanford used genetic and biochemical methods to investigate the control of swarming and multiplication behavior of the bacterium Myxococcus , which forms a fruiting body with roughly spores in the event of unfavorable environmental conditions . They succeeded in identifying and elucidating the role of a number of messenger substances involved.

In 1970 he received the Molecular Biology Award from the US Steel Foundation , 1980 the Albert Lasker Award for Basic Medical Research , 1981 the Waterford Biomedical Science Award, 1997 the Abbott Lifetime Achievement Award from the American Society for Microbiology and in 1991 the Thomas Hunt Morgan Medal . In 1970 he became a member of the National Academy of Sciences and the American Academy of Arts and Sciences . In 1993 Kaiser was President of the Genetics Society of America .

Fonts

  • Editor with Martin Dworkin Myxobacteria II , American Society of Microbiology 1993
  • Editor with Graham C. Walker Frontiers in Microbiology , American Society of Microbiology 1993

Web links

Individual evidence

  1. Date of birth according to American Men and Women of Science , Thomson Gale 2004
  2. Bruce Goldman: Dale Kaiser, founding member of Stanford's Department of Biochemistry, dies at 92nd Stanford University School of Medicine, June 23, 2020, accessed June 23, 2020 .