The genus Betapapillomavirus groups together viruses from the Papillomaviridae family that cause skin infections in humans. Infections with viruses of this genus are widespread in the population, but in the sense of a latent infection that usually remains clinically without symptoms. The species HPV-5, HPV-9 and HPV-49 are associated with the development of epidermodysplasia verruciformis , a disease with the proliferation of multiple warts and papillomas . In contrast to the alpha papilloma viruses, the virus species of the genus Betapapillomavirus completely lack the gene for the viral E5 protein. In addition to the isolates in humans, an independent, as yet unclassified beta- papilloma virus species has been isolated from long-tailed macaques , in which the virus causes rapidly progressing papillomatosis of the paws.
Systematics
The systematics of the genus Betapapillomavirus has since been reorganized ( ICTV status November 2018) into species names Betapapillomavirus 1 to 6 . Here is the previous taxonomy:
E.-M. de Villiers, et al. : Genus Betapapillomavirus . In: CM Fauquet, MA Mayo et al. : Eighth Report of the International Committee on Taxonomy of Viruses . London, San Diego, 2005 pp. 245ff, ISBN 0-122-49951-4
Peter M. Howley , Douglas R. Lowy: Papillomaviruses . In: David M. Knipe, Peter M. Howley (eds.-in-chief): Fields' Virology . 5th edition, Volume 2, Philadelphia 2007, pp. 2299ff, ISBN 0-781-76060-7
↑ J. Joh, K. Hopper et al. : Macaca fascicularis papillomavirus type 1: a non-human primate betapapillomavirus causing rapidly progressive hand and foot papillomatosis. In: The Journal of general virology. Volume 90, April 2009, ISSN 0022-1317 , pp. 987-994, doi : 10.1099 / vir.0.006544-0 , PMID 19264664 .
