Brigitte Mayinger

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Brigitte Mayinger (* 1962 in Munich ) is a German internist and adjunct professor at the University of Erlangen-Nuremberg. She is chief physician for internal medicine II at the Munich West Clinic. Mayinger is known for developing new diagnostic procedures that are interdisciplinary and based on bio-medical-physical and optical methods for early tumor diagnosis in gastroenterological endoscopy . She is the daughter of the thermodynamicist Franz Mayinger .

Life

After graduating from the humanistic Kaiser Wilhelm High School in Hanover , Mayinger studied human medicine at the Albert Ludwigs University in Freiburg and the Ludwig Maximilians University in Munich (1981–1986) and qualified as a doctor in 1987. In 1986 she passed the American State Examination for Foreign Medicines (ECFMG). After three stays as a visiting doctor in the departments of endocrinology, gastroenterology and cardiology at the Beth-Israel Hospital of Harvard Medical School in Boston, she began her training as an internist at the 2nd Medical Clinic of the Augsburg Central Hospital . In 1997 she acquired the specialization title for gastroenterology and in 2003 for endocrinology at the 1st Medical Clinic of the Friedrich-Alexander University Erlangen-Nuremberg. She is trained as a diabetologist DDG and palliative medicine specialist. Mayinger completed her habilitation in 2001 on the subject of "Light-induced autofluorescence spectroscopy of carcinomas of the esophagus and stomach: development, validation and clinical application" at the Friedrich-Alexander University Erlangen-Nuremberg . She completed her medical economics studies at the University of Bayreuth with a degree in medical economics (2002) and an MBA Business Health Administrator (2008). Mayinger has been the chief physician of the Medical Clinic II since 2004 and the deputy medical director of the Munich West Clinic since 2006. In 2008 she was appointed adjunct professor with teaching activities at the University of Erlangen-Nuremberg.

Scientific contribution

B. Mayinger's scientific work focused on clinically applied research areas.

Mayinger's first clinical work dealt with the clinical application and evaluation of a flexible endoscope system with a disposable protective cover that is currently being developed against the background of hygienic aspects and handling.

The main research focus was the endoscopic early detection of gastroenterological tumors using light-optical methods such as autofluorescence spectroscopy and photodynamic diagnostics . In cooperation with employees of the Technical University of Munich and a manufacturer of medical technology products, autofluorescence spectroscopy was developed and later used in clinical use in endoscopic examinations for the detection of carcinomas of the esophagus , stomach and colon. With the help of special light-optical excitation methods and highly sensitive measurement methods, it was possible to work out different light-optical behaviors of various gastrointestinal tumors in vivo.

Another focus was photodynamic diagnostics in the upper and lower gastrointestinal tract. In cooperation with the development department of Karl Storz Endoskope and a Norwegian company, the endoscopic light-optical early detection of colon polyps and cancer was carried out with the help of an enterally applied tumor-affine photosensitizer.

In collaboration with the Fraunhofer IIS Institute at the University of Erlangen, she worked on the evaluation of computer-aided image analysis methods to differentiate between cardia and Barrett's mucosa with or without intraepithelial neoplasia, with the aim of facilitating early tumor detection.

Memberships in scientific associations

Web links

Individual evidence

  1. a b Internal Medicine II, HELIOS Clinic Munich West. (No longer available online.) HELIOS Clinic Munich West, archived from the original on September 8, 2017 ; accessed on August 26, 2017 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.helios-kliniken.de
  2. Disposable protective cover for flexible gastroenterological endoscopy: prospective comparative evaluation of a new gastroscope system (endosheath) compared to the standard glass fiber gastroscope. Mayinger B, Strenkert M, Martus P, Kunz B, Hahn EG, Hochberger J.Z Gastroenterol, 36 (1998); 501-507.
  3. ^ Disposable-sheath, flexible gastroscope system versus standard gastroscopes: a prospective, randomized trial. Mayinger B, Strenkert M, Hochberger J, Martus P, Kunz B, Hahn EG. Gastrointest Endosc, 50 (1999); 461-467.
  4. Fluorescence spectroscopy for premalignant and malignant lesions in the upper gastrointestinal tract - Medical aspects and recent advances. Mayinger B, Horner P, Jordan M, Gerlach C, Horbach T, Hohenberger W, Hahn EG. Medical & Biological Engineering & Computing, 37 (2) (1999); 1556-1557.
  5. Fluorescence spectroscopy for premalignant and malignant lesions in the upper gastrointestinal tract - Technical background. Horner P, Mayinger B, Jordan M, Gerlach C, Horbach T, Hohenberger W, Hahn EG. Medical & Biological Engineering & Computing, 37 (2) (1999); 1558-1559.
  6. Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of gastrointestinal cancer and dysplastic lesions. Mayinger B, Reh H, Hochberger J, Hahn EG. Gastrointest Endosc, 50 (1999); 242-246.
  7. Fluorescence endoscopy induced with 5-aminolevulinic acid for the detection and follow-up of esophageal lesions. Mayinger B, Neidhardt S, Reh H, Martus P, Hahn EG. Gastrointest Endosc, 54 (2001); 572-578.
  8. Light-induced autofluorescence spectroscopy for the endoscopic detection of esophageal carcinoma. Mayinger B, Horner P, Jordan M, Gerlach C, Horbach T, Hohenberger W, Hahn EG. Gastrointest Endosc, 54 (2001); 195-201.
  9. ^ Evaluation of endoscopic fluorescence spectroscopy for the diagnosis of gastrointestinal cancer and dysplasia. Mayinger B, Jordan M, Horner P, Gerlach C, Horbach T, Guenther K, Hohenberger W, Hahn EG. International Federation for Medical and Biological Engineering Proceedings, 3 (2) (2002); 1110-1111.
  10. Early detection of (pre-) malignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate (HAL). Mayinger B, Neumann F, Kastner C, Degitz K, Hahn EG, Schwab D. Endoscopy. 2008 Feb; 40 (2): 106-9. doi : 10.1055 / s-2007-967019 .
  11. Hexaminolevulinate-induced fluorescence colonoscopy versus white light endoscopy for diagnosis of neoplastic lesions in the colon. Mayinger B, Neumann F, Kastner C, Haider T, Schwab D. Endoscopy. 2010 Jan; 42 (1): 28-33.
  12. Color-texture-based optical biopsy on high-resolution endoscopic color images of the esophagus. Munzenmayer C, Mühldorfer S, Mayinger B, Volk H, Grobe M, Wittenberg T. In image processing for medicine 2003: Algorithms - Systems - Applications. Springer-Verlag Berlin 2003, ISBN 3-540-00619-2 , 191-195.
  13. Linear color correction for automatic tissue recognition in endoscopy of the esophagus. Munzenmayer M, Naujokat F, Mühldorfer S, Mayinger B, Wittenberg T. In Tolxdorff et al. (Ed.): Image processing for medicine 2004, series Informatik Aktuell, Springer-Verlag Berlin 2004, ISBN 3-540-21059-8 ; 15-19.