Centrophenoxine

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Structural formula
Structural formula of centrophenoxine
General
Non-proprietary name Meclofenoxate
other names
  • 2- (Dimethylamino) ethyl- (4-chlorophenoxy) acetate ( IUPAC )
  • Centrophenoxine
Molecular formula C 12 H 16 ClNO 3
External identifiers / databases
CAS number
  • 51-68-3
  • 3685-84-5 (hydrochloride)
EC number 200-116-3
ECHA InfoCard 100,000,107
PubChem 4039
ChemSpider 3899
Wikidata Q421147
Drug information
ATC code

N06 BX01

Drug class

Stimulant , nootropic

properties
Molar mass 257.71 g mol −1
Physical state

firmly

Melting point

137–140 ° C (hydrochloride)

safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
07 - Warning

Caution

H and P phrases H: 302-315-319-335
P: 261-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Centrophenoxine (also meclofenoxate ) is a carboxylic acid ester of dimethylaminoethanol . A substituted phenoxyacetic acid , 4-chlorophenoxyacetic acid, occurs as the acid component .

It is a discontinued drug used to treat the symptoms of senile dementia and Alzheimer's disease . A reduction in the age-related degradation product lipofuscin was only suspected in animal experiments. In Germany, the substance is on the list of substances whose export is monitored because it can potentially be used to manufacture chemical weapons.

Side effects

Difficulty falling asleep, confusion

Individual evidence

  1. a b c data sheet Centrophenoxine hydrochloride from Sigma-Aldrich , accessed on March 16, 2011 ( PDF ).