Cytidine triphosphate

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Structural formula
Structural formula of CTP
General
Surname Cytidine triphosphate
other names
  • Cytidine 5'-triphosphate
  • CTP
  • [(2 R , 3 S , 4 R , 5 R ) -5- (4-amino-2-oxopyrimidin-1-yl) -3,4-dihydroxyoxolan-2-yl] methyl (hydroxy-phosphonooxyphosphoryl) hydrogen phosphate ( IUPAC )
Molecular formula C 9 H 16 N 3 O 14 P 3
External identifiers / databases
CAS number 65-47-4
EC number 200-611-4
ECHA InfoCard 100,000,556
PubChem 6176
ChemSpider 19952488
DrugBank DB02431
Wikidata Q409648
properties
Molar mass 483.16 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cytidine triphosphate ( CTP ) is a nucleoside triphosphate with the base cytosine . It is an RNA building block that is incorporated into the RNA by splitting off two phosphate groups .

CTP can bind phosphocholine by splitting off pyrophosphate and then transfer it to another molecule, e.g. B. on a diglyceride . This creates a phosphatide . Accordingly, CTP and CDP-choline (cytidine diphosphate choline) play a role in phosphatide synthesis. CTP also inhibits aspartate transcarbamoylase in pyrimidine biosynthesis .

Other ribonucleoside triphosphates are adenosine triphosphate (ATP), guanosine triphosphate (GTP) and uridine triphosphate (UTP).

Individual evidence

  1. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. Jeremy M. Berg, Lubert Stryer, John L. Tymoczko: Stryer Biochemistry. ISBN 3827429889 p. 292 ( limited preview in Google Book Search).