Edmund Speyer

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Edmund Speyer around 1920

Jakob Edmund Speyer (born November 11, 1878 in Frankfurt am Main ; † May 5, 1942 in Łódź ) was a German university professor and chemist of Jewish descent.

Career

Structural formula of oxycodone

Speyer was born the son of the Frankfurt businessman M. Speyer. After graduating from high school in Frankfurt in 1896, he began studying chemistry at the Ruprecht-Karls-Universität Heidelberg . Here he was at Emil Knoevenagel in July 1901 with a thesis to note the addition of unsaturated compounds ability doctorate .

Then Speyer went back to Frankfurt, where he initially worked as a research assistant at the University of Frankfurt. In 1915 he received his habilitation with contributions to the knowledge of thebaine and its derivatives . With Martin Freund , who was head of the chemical institute at the Physikalischer Verein , he synthesized the opioid oxycodone for the first time in 1916. Oxycodone was marketed by Merck in Darmstadt in 1917 under the brand name Eukodal as a pain reliever and cough suppressant.

He then worked as a private lecturer and from 1932 as an associate professor on the research of alkaloids; Numerous patents and publications testify to the successful collaboration between Freund and Speyer between 1902 and 1920. He wrote the Nekrolog for Martin Freund.

A year later, after the National Socialists came to power, his license to teach was revoked because of his Jewish faith.

Speyer was later deported to the Litzmannstadt ghetto in Łódź . On May 4, 1942, the first transport with 1,000 of the “newly settled” from Berlin, Cologne, Frankfurt, Prague, Paris, etc., from the Radogoszcz train station , whose backpacks, bread bags and wedding rings had previously been removed in the police prison, left the station: This news had had a depressing effect throughout the ghetto. Speyer died on May 5, 1942 of "heart failure" and "exhaustion".

On October 17, 2014, on the occasion of the 100th birthday of Goethe University , a stumbling block was laid for him at Unterweg 22.

Stumbling block for Dr. Edmund Speyer on Unterweg 22

Publications (selection)

  • E. Speyer, H. Wieters: Contribution to the knowledge of Codeinoxyd-sulfonic acids and their derivatives. In: Reports of the German Chemical Society. Volume 54, Number 11, 1921, pp. 2976-2987. doi : 10.1002 / cber.19210541106
  • E. Speyer, AG Becker: About the action of hydrogen peroxide on china alkaloids. In: Reports of the German Chemical Society. Volume 55, Number 5, 1922, pp. 1321-1329. doi : 10.1002 / cber.19220550523
  • E. Speyer, G. Becker: On the knowledge of morphine. In: Reports of the German Chemical Society. Volume 55, Number 5, 1922, pp. 1329-1339. doi : 10.1002 / cber.19220550524
  • E. Speyer, K. Koulen: On the action of ozone on des-N-methyl-dihydro-kodein (I. Commun.). In: Reports of the German Chemical Society. Volume 64, number 11, 1931, pp. 2815–2819 doi : 10.1002 / cber.19310641110 as the last publication.

Web links

Commons : Edmund Speyer  - Collection of images, videos and audio files
Wikisource: Edmund Speyer  - Sources and full texts

Individual evidence

  1. ^ Inaugural dissertation, University of Heidelberg, 1901. - as well as E. Knoevenagel and E. Speyer: About the condensing effect of organic bases . In: Reports of the German Chemical Society 35, 395-399 (1902). doi : 10.1002 / cber.19020350165
  2. M. Freund, E. Speyer: About the conversion of thebaine into oxycodeinone and its derivatives. In: Journal for Practical Chemistry. Volume 94, number 1, 1917, pp. 135-178. doi : 10.1002 / prac.19160940112
  3. ^ J. Friedman: The Lion and the Star. University Press of Kentucky, 1998, ISBN 0-813-12043-8 , p. 238. Restricted preview in Google Book Search
  4. W. Killy: Dictionary of German Biography. Volume 9 (Schmidt - Theyer), Walter de Gruyter, 2005, ISBN 3-110-96629-8 , p. 409. Restricted preview in the Google book search
  5. ^ S. Feuchert, E. Leibfried, J. Riecke: Chronicle of the Ghetto Lodz / Litzmannstadt . Wallstein Verlag, 2007, ISBN 3-892-44834-5 , p. 146; P. 650f.
  6. ^ L. Dobroszycki: The Chronicle of the Lodz Ghetto, 1941-1944. Yale University Press, 1987, ISBN 0-300-03924-7 , p. 176. Restricted preview in Google Book Search
  7. ^ S. Feuchert, E. Leibfried, J. Riecke: Chronicle of the Ghetto Lodz / Litzmannstadt . Wallstein Verlag, 2007, ISBN 3-892-44834-5 , p. 201; P. 670. Limited preview in Google Book search