Iron (II) fumarate

Structural formula
General
Surname	Iron (II) fumarate
other names	Iron (II) - ( E ) -but-2-endioate ( IUPAC ) Feostat
Molecular formula	FeC 4 H 2 O 4
Brief description	red-brown powder
External identifiers / databases
CAS number 141-01-5 EC number 205-447-7 ECHA InfoCard 100,004,953 PubChem 6433164 Wikidata Q416370
Drug information
ATC code	B03 AA02
properties
Molar mass	169.90 g mol −1
Physical state	firmly
density	1.44 g cm −3
Melting point	279-281 ° C
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
Toxicological data	3850 mg kg −1 ( LD 50 ,  rat ,  oral )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Iron (II) fumarate is a divalent iron salt of fumaric acid and is used for oral replacement therapy in iron deficiency anemia .

Biological importance

Iron is only absorbed in the intestine in its bivalent form. The drug should be taken on an empty stomach, as this is where iron absorption is greatest. However, gastrointestinal complaints can occur in sensitive patients. Antacids can also inhibit iron absorption. In this case, it makes sense to divide the dose into several individual doses.

literature

• The MSD Manual for Diagnostics and Therapy p. 1254 Elsevier 2007 ISBN 3-437-21761-5

Individual evidence

1. ↑ ^{a b c d} Datasheet Ferrous fumarate from Sigma-Aldrich , accessed on March 29, 2011 ( PDF ).
2. ↑ Data sheet iron (II) fumarate from AlfaAesar, accessed on December 15, 2010 ( PDF )(JavaScript required) .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !