Erwin F. Wagner
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Erwin Friedrich Wagner (born November 25, 1950 in Wolfsberg , Carinthia ) is an Austrian biochemist and genetic researcher . Among other things, he is known for uncovering the function and importance of AP-1 (Fos / Jun) in the development of mice and in various diseases.
Life
Erwin Wagner was born in Wolfsberg . From 1974 he studied technical chemistry at the University of Graz and graduated in 1974 with an engineering degree. In 1975 he worked in Fritz Paltauf's laboratory on lipid chemistry .
During his doctoral studies, Erwin Wagner joined the Max Planck Institute for Molecular Genetics in Berlin for one year in 1976 , and in 1977 he joined Manfred Schweiger's laboratory at the University of Innsbruck . Wagner received his doctorate in 1978 with a thesis on "Regulation of gene expression after virus infections".
In 1979 Erwin Wagner started his postdoc research at the Fox Chase Cancer Center in Philadelphia , USA, in Beatrice Mintz's laboratory as a Max Kade Fellow. Wagner's work focused on the genetic control of mouse development to develop techniques that allow the microinjection of DNA into fertilized eggs, as well as the development of gene transfer technologies in stem cells and mice.
In 1983 Wagner received his habilitation from the University of Innsbruck and became group leader at the European Molecular Biology Laboratory (EMBL) in Heidelberg .
In 1988 Wagner was appointed Senior Scientist at the then newly founded Research Institute for Molecular Pathology (IMP) in Vienna . Wagner was a founding member of the IMP and its deputy director from 1997 to 2008.
In 2008, Wagner left the IMP to become Associate Director and Head of the Cancer Cell Biology Program at the Spanish National Cancer Research Center (CNIO) in Madrid , Spain. In 2018 Wagner left CNIO and returned to Vienna in January 2019, where he works as group leader in the Department of Dermatology and Laboratory Medicine at the Medical University of Vienna.
He is a member of the editorial board of "Developmental Cell".
research
Erwin Wagner's studies focus on the area of gene function in healthy and pathological conditions. His work focuses on the areas of cancer biology and tumor development. He investigates the functions of transcription factor complexes that regulate cell proliferation, differentiation and oncogenesis as well as crosstalk between organs in both mice and humans. He works to define and understand the molecular mechanisms that lead to disease and cancer development, and works to identify new therapeutic targets for the treatment of human diseases.
Awards (selection)
- 1988 member of the European Molecular Biology Organization
- 1993 Max Planck Research Prize
- 1996 Wittgenstein Prize of the Republic of Austria
- 1998 member of the Academia Europaea
- 2003 Prize of the Charles Rodolphe Brupbacher Foundation
- 2005 member of the Austrian Academy of Sciences
literature
- Erwin F. Wagner. In: Oncogene. 20, 2001, p. 2333, doi: 10.1038 / sj.onc.1204415 .
Web links
- Genes, Development and Disease Group and Biosketch: Erwin Wagner at the Centro Nacional de Investigaciones Oncologica (cnio.es)
- CV (as of 2005; PDF; 65 kB) at Academia Europaea (ae-info.org)
- Erwin Wagner, 1996 Wittgenstein Prize Winner at the Fund for the Promotion of Scientific Research (fwf.ac.at)
Individual evidence
- ↑ Erwin F. Wagner. In: people.embo.org. European Molecular Biology Organization , accessed September 28, 2018 .
- ↑ Wagner, Erwin. In: ae-info.org. Academia Europaea , September 1, 2015, accessed September 28, 2018 .
- ^ Brupbacher Prize. In: brupbacher-foundation.org. Charles Rodolphe Brupbacher Foundation , accessed on April 9, 2019 .
- ↑ Erwin Wagner. In: oeaw.ac.at. Austrian Academy of Sciences , accessed on September 28, 2018 .
| personal data | |
|---|---|
| SURNAME | Wagner, Erwin F. |
| ALTERNATIVE NAMES | Wagner, Erwin Friedrich; Wagner, Erwin |
| BRIEF DESCRIPTION | Austrian biochemist and geneticist |
| DATE OF BIRTH | November 25, 1950 |
| PLACE OF BIRTH | Wolfsberg , Carinthia |